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Mostrando publicaciones 1-5 de 5

  • Alzheimer's disease susceptibility gene Apolipoprotein E (APOE) and blood biomarkers in UK Biobank (N = 395,769) 

    Ferguson, Amy C.; Tank, Rachana; Lyall, Laura M.; Ward, Joey; Celis-Morales, Carlos; Strawbridge, Rona; Ho, Frederick; Whelan, Christopher D.; Gill, Jason M.R.; Welsh, Paul; Anderson, Jana J.; Mark, Patrick B.; Mackay, Daniel; Smith, Daniel J.; Pell, J.P.; Cavanagh, Jonathan; Sattar, Naveed; Lyall, Donald (2020)
    Background: Alzheimer's disease (AD) is a neurodegenerative condition where the underlying etiology is still unclear. Investigating the potential influence of apolipoprotein E (APOE), a major genetic risk factor, on common ...

  • Associations between physical frailty and dementia incidence: a prospective study from UK Biobank 

    Petermann-Rocha, Fanny; Lyall, Donald; Gray, S.R.; Esteban-Cornejo, Irene; Quinn, Terence J.; Ho, Frederick; Pell, J.P.; Celis-Morales, Carlos (2020)
    Background: Dementia is associated with a high burden of dependency and disability. Physical frailty (hereafter referred to as frailty) is a multisystem dysregulation that has been identified as a risk factor for dementia. ...

  • Associations of fat and carbohydrate intake with cardiovascular disease and mortality: prospective cohort study of UK Biobank participants 

    Ho, Frederick; Gray, S.R.; Welsh, Paul; Petermann-Rocha, Fanny; Foster, Hamish M. E.; Waddell, Heather; Anderson, Jana J.; Lyall, Donald; Sattar, Naveed; Gill, Jason M.R.; Mathers, John; Pell, J.P.; Celis-Morales, Carlos (2020)
    Objective: To investigate the association of macronutrient intake with all cause mortality and cardiovascular disease (CVD), and the implications for dietary advice. Design: Prospective population based study. Setting: ...

  • Child maltreatment and cardiovascular disease: quantifying mediation pathways using UK biobank 

    Ho, Frederick; Celis-Morales, Carlos; Gray, S.R.; Petermann-Rocha, Fanny; Lyall, Donald; Mackay, Daniel; Sattar, Naveed; Minnis, Helen; Pell, J.P. (2020)
    Background: Child maltreatment is associated with cardiovascular disease (CVD), but mediation pathways have not been fully elucidated. The aim of the current study was to determine and quantify the underlying pathways ...

  • Comparison of two different frailty measurements and risk of hospitalisation or death from COVID-19: findings from UK Biobank 

    Petermann-Rocha, Fanny; Hanlon, Peter; Gray, S.R.; Welsh, Paul; Gill, Jason M.R.; Foster, Hamish M. E.; Katikireddi, Vittal S.; Lyall, Donald; Mackay, Daniel; O’Donnell, Catherine A.; Sattar, Naveed; Nicholl, Barbara I.; Pell, J.P.; Jani, Bhautesh D.; Ho, Frederick; Mair, Frances S.; Celis-Morales, Carlos (2020)
    Background. Frailty has been associated with worse prognosis following COVID-19 infection. While several studies have reported the association between frailty and COVID-19 mortality or length of hospital stay, there have ...