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Exploring the interplay between polyphenols and lysyl oxidase enzymes for maintaining extracellular matrix homeostasis
Collagen, the most abundant structural protein found in mammals, plays a vital role as a constituent of the extracellular matrix (ECM) that surrounds cells. Collagen fibrils are strengthened through the formation of ...
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Lysyl oxidase like-2 crosslinks collagen IV of glomerular basement membrane
Añazco-Oyarzún, Carolina; López-Jiménez, Alberto J.; Rafi, Mohamed; Vega-Montoto, Lorenzo; Zhang, Ming-Zhi; Hudson, Billy G.; Vanacore, Roberto M. (2016)The 7S dodecamer is recognized as an important structural crosslinking domain of collagen IV networks that provide mechanical stability to basement membranes, a specialized form of extracellular matrix essential for the ...