Listar Artículos Científicos por autor
Mostrando publicaciones 1-14 de 14
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A peptide backbone stapling strategy enabled by the multicomponent incorporation of amide n-substituents
Ricardo, Manuel G.; Marrrero, Javiel F.; Valdés, Oscar; Rivera, Daniel G.; Wessjohann, Ludger A. (2019)The multicomponent backbone N-modification of peptides on solid-phase is presented as a powerful and general method to enable peptide stapling at the backbone instead of the side chains. This work shows that a variety of ...
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Comparative study of three dyes’ adsorption onto activated carbon from chenopodium quinoa willd and quillaja saponaria
Abril, Diana ; Ferrer, Victor; Mirabal-Gallardo, Yaneris; Cabrera-Barjas, Gustavo; Segura, Cristina; Marican, Adolfo; Pereira, Alfredo; Durán-Lara, Esteban F.; Valdés, Oscar (2022)The present study shows porous activated carbon obtained from Chenopodium quinoa Willd and Quillaja saponaria and their use as potential adsorbents to remove three types of dyes from aqueous solutions. The adsorption results ...
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Comparison of the oxidative stability and antioxidant activity of extra-virgin olive oil and oils extracted from seeds of Colliguaya integerrima and Cynara cardunculus under normal conditions and after thermal treatment
abril, diana ; Mirabal-Gallardo, Yaneris; González, Aymeé; Marican, Adolfo; Durán-Lara, Esteban F.; Silva Santos, Leonardo; Valdés, Oscar (2019)We investigated the potential of two oil extracts from seeds of Colliguaya integerrima (CIO) and Cynara cardunculus (CO) to use as nutritionally edible oils. For this purpose, oil quality was accessed by determining the ...
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Development and evaluation of cross-linked alginate–chitosan–abscisic acid blend gel
Bustos, Daniel; Guzmán, L.; Valdés, Oscar; Muñoz-Vera, Marcelo; Morales-Quintana, Luis; Castro, Ricardo I. (2023)Abscisic acid (ABA) has been proposed to play a significant role in the ripening of noncli macteric fruit, stomatal opening, and response to abiotic stresses in plants, which can adversely affect crop growth and productivity. ...
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Development of “on-demand” thermo-responsive hydrogels for anti-cancer drugs sustained release: rational design, in silico prediction and in vitro validation in colon cancer models
Carreño, Gustavo; Pereira, Alfredo; Ávila-Salas, Fabián; Marican, Adolfo; Andrade, Fernanda; Roca-Melendres, Maria; Valdés, Oscar; Vijayakumar, Sekar; Schwartz Jr, Simó; Abasolo, Ibane; Rafael, Diana; Durán-Lara, Esteban F. (2021)A rational design accurate based on the use of Statistical Design of the Experiments (DoE) and Molecular Dynamics Simulations Studies allows the prediction and the understanding of thermo-responsive hydrogels prepared ...
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Effect of cellulose nanofibrils on vancomycin drug release from chitosan nanocomposite films
Cabrera-Barjas, Gustavo; Becheran, Liliam; Valdés, Oscar; Giordano, Ady; Segura-del Río, Rodrigo; Bravo-Arrepol, Gastón; Durán-Lara, Esteban F.; Cea, Juan; Berg, Alex; Castaños, Johana; Rodríguez-Llamazares, Saddys; Fuentes, Gastón; Katsarov, Plamen; Lukova, Paolina; Delattre, Cédric (2023)Overuse of antibiotic drugs usually leads to the further development of resistance to targeted bacteria. In this context, a controlled release system could be a solution to achieve higher drug efficiency without overdosing ...
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Multicomponent reactions in ligation and bioconjugation chemistry
Reguera, Leslie; Méndez, Yanira; Humpierre, Ana R.; Valdés, Oscar; Rivera, Daniel G. (2018)Multicomponent reactions (MCRs) encompass an exciting class of chemical transformations that have proven success in almost all fields of synthetic organic chemistry. These convergent procedures incorporate three or more ...
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Polyaniline based materials as a method to eliminate haloanisoles in spirits beverages
Valdés, Oscar; Marican, Adolfo; Avila-Salas, Fabian; Castro, R. I.; Amalraj, John; Laurie, Felipe; Santos, Leonardo S. (2018)In this research, the abilities of two polyaniline-based materials (PANI-EB and PANI-ES) were evaluated as potential fining agents to eliminate 2,4,6-trichloroanisole (TCA) and 2,4,6-tribromoanisole (TBA). The results ...
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Rational design of hydrogels for cationic antimicrobial peptide delivery: a molecular modeling approach
Pereira, Alfredo; Valdés-Muñoz, Elizabeth; Marican, Adolfo; Cabrera-Barjas, Gustavo; Vijayakumar, Sekar; Valdés, Oscar; Rafael, Diana; Andrade, Fernanda; Abaca, Paulina; Bustos, Daniel; Durán-Lara, Esteban F. (2022)In light of the growing bacterial resistance to antibiotics and in the absence of the development of new antimicrobial agents, numerous antimicrobial delivery systems over the past decades have been developed with the aim ...
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Rational design, synthesis and evaluation of γ-CD-containing cross-linked polyvinyl alcohol hydrogel as a prednisone delivery platform
Marican, Adolfo; Avila-Salas, Fabian; Valdés, Oscar; Wehinger, Sergio; Villaseñor, Jorge; Fuentealba, Natalia; Arenas-Salinas, Mauricio; Argandoña, Yerko; Carrasco-Sánchez, Verónica; Durán-Lara, Esteban F. (2018)This study describes the in-silico rational design, synthesis and evaluation of cross-linked polyvinyl alcohol hydrogels containing γ-cyclodextrin (γ-CDHSAs) as platforms for the sustained release of prednisone (PDN). ...
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Selective and efficient arsenic recovery from water through quaternary amino-functionalized silica
Valdés, Oscar; Marican, Adolfo; Mirabal-Gallardo, Yaneris; Santos, Leonardo S. (2018)The free-radical graft polymerization of acryloxyethyl-trimethylammonium chloride onto commercial silica particles was studied experimentally for extraction of arsenic ions from water. Two steps were used to graft ...
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Simple approach for cleaning up 2,4,6-trichloroanisole from alcoholic-beverage-reconstituted solutions using polymeric materials
Valdés, Oscar; Marican, Adolfo; Avila-Salas, Fabian; Castro, R. I.; Mirabal-Gallardo, Yaneris; Amalraj, John; abril, diana ; Durán-Lara, Esteban F.; Santos, Leonardo S. (2019)Background and Aims: 2,4,6-Trichloroanisole (TCA) is a well-recognised contaminant in the wine and whisky industries. In this work, several polymeric materials were tested through a hybrid strategy (computational and ...
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Ugi reaction-derived prolyl peptide catalysts grafted on the renewable polymer polyfurfuryl alcohol for applications in heterogeneous enamine catalysis
De la Torre, Alexander F.; Scatena, Gabriel S.; Valdés, Oscar; Rivera, Daniel G.; Paixão, Márcio W. (2019)The multicomponent synthesis of prolyl pseudo-peptide catalysts using the Ugi reaction with furfurylamines or isocyanides is described. The incorporation of such a polymerizable furan handle enabled the subsequent ...
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Valorization of food waste to produce intelligent nanofibrous β-chitin films
Cabrera-Barjas, Gustavo; Radovanović, Neda; Bravo, Gaston; De la Torre, Alexander F.; Valdés, Oscar; Nesic, Aleksandra (2021)The efficient use of waste from food processing industry is one of the innovative approaches within sustainable development, because it can be transferred into added value products, which could improve economic, energetic ...