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Mostrando publicaciones 1-7 de 7
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ABCB1/4 gallbladder cancer risk variants identified in India also show strong effects in Chileans
Boekstegers, Felix; Marcelain, Katherine; Barahona-Ponce, Carol; Baez Benavides, Pablo F.; Müller, Bettina; De Toro, Gonzalo; Retamales, Javier; Barajas, Olga; Ahumada, Monica; Morales, Erik; Rojas, Armando ; Sanhueza, Verónica; Loader, Denisse; Rivera, María T.; Gutiérrez, Lorena; Bernal, Giuliano; Ortega, Alejandro; Montalvo, Domingo; Portiño, Sergio; Bertrán, María E.; Gabler, F.; Spencer, Loreto; Olloquequi, Jordi; González-Silos, Rosa; Fischer, Christine; Scherer, Dominique; Jenab, Mazda; Aleksandrova, Krasimira; Katzke, Verena; Weiderpass, Elisabete; Moradi, Tahereh; Fischer, Krista; Bossers, Willem; Brenner, Hermann; Hveem, Kristian; Eklund, Niina; Völker, Uwe; Waldenberger, Melanie; Fuentes-Guajardo, Macarena; González-José, Rolando; Bedoya, Gabriel; Bortolini, María C.; Canizales, Samuel; Gallo, Carla; Ruiz-Linares, Andres; Rothhammer, Francisco; Lorenzo-Bermejo, Justo (2020)Background: The first large-scale genome-wide association study of gallbladder cancer (GBC) recently identified and validated three susceptibility variants in the ABCB1 and ABCB4 genes for individuals of Indian descent. ...
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Epigenome-wide analysis of methylation changes in the sequence of gallstone disease, dysplasia, and gallbladder cancer
Brägelmann, Johannes; Barahona-Ponce, Carol; Marcelain, Katherine; Roessler, Stephanie; Goeppert, Benjamin; Gallegos, Ivan; Colombo, Alicia; Sanhueza, Verónica; Morales, Erik; Rivera, María T.; De Toro, Gonzalo; Ortega, Alejandro; Müller, Bettina; Gabler, F.; Scherer, Dominique; Waldenberger, Melanie; Reischl, Eva; Boekstegers, Felix; Garate-Calderon, Valentina; Umu, Sinan U.; Rounge, Trine B.; Popanda, Odilia; Lorenzo-Bermejo, Justo (2021)Background and Aims: Gallbladder cancer (GBC) is a highly aggressive malignancy of the biliary tract. Most cases of GBC are diagnosed in low-income and middle-income countries, and research into this disease has long been ...
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Gallstones, body mass index, C-reactive protein, and gallbladder cancer: Mendelian randomization analysis of Chilean and European genotype data
Barahona-Ponce, Carol; Scherer, Dominique; Brinster, Regina; Boekstegers, Felix; Marcelain, Katherine; Gárate-Calderón, Valentina; Müller, Bettina; De Toro, Gonzalo; Retamales, Javier; Barajas, Olga; Ahumada, Monica; Morales, Erik; Rojas, Armando ; Sanhueza, Verónica; Loader, Denisse; Rivera, María T.; Gutiérrez, Lorena; Bernal, Giuliano; Ortega, Alejandro; Montalvo, Domingo; Portiño, Sergio; Bertrán, María E.; Gabler, F.; Spencer, Loreto; Olloquequi, Jordi; Fischer, Christine; Jenab, Mazda; Aleksandrova, Krasimira; Katzke, Verena; Weiderpass, Elisabete; Bonet, Catalina; Moradi, Tahereh; Fischer, Krista; Bossers, Willem; Brenner, Hermann; Hveem, Kristian; Eklund, Niina; Völker, Uwe; Waldenberger, Melanie; Fuentes-Guajardo, Macarena; González-José, Rolando; Bedoya, Gabriel; Bortolini, María C.; Canizales, Samuel; Gallo, Carla; Ruiz-Linares, Andres; Rothhammer, Francisco; Lorenzo-Bermejo, Justo (2021)Background and Aims: Gallbladder cancer (GBC) is a neglected disease with substantial geographical variability: Chile shows the highest incidence worldwide, while GBC is relatively rare in Europe. Here, we investigate the ...
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Gastric tumor microenvironment
A compelling body of evidence has demonstrated that gastric cancer has a very particular tumor microenvironment, a signature very suitable to promote tumor progression and metastasis. Recent investigations have provided ...
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Pathogenic potential of Helicobacter pylori strains can explain differences in H. pylori associated diseases rates from Chile and Cuba
González-Bonet, Ileana; González, Lidice; Rojas, Armando ; Rodríguez, Boris L.; Romero, Jacqueline; Reyes, Orlando; Morales, Erik; Alonso, Jordis; Pérez-Castro, Ramón; Sabatier, Carlos A.; Valdés, Eliana; Torres, Linio E.; Cofré, Cecilia (2019)Background: The prevalence of Helicobacter pylori-related diseases varies geographically and it is partially determined by the virulence of the circulating strains. Cuba and Chile exhibit different gastric cancer rates, ...
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Totally laparoscopic radical cholecystectomy (lymphadenectomy and segment IVb-V liver resection) after incidental gallbladder carcinoma (with video)
Muñoz-Castro, César A.; Marino-Coloma, Carlo; Morales, Erik (2018) -
Validation of an NGS panel designed for detection of actionable mutations in tumors common in Latin America
Salvo, Mauricio; González-Feliú, Evelin; Toro, Jessica; Gallegos, Ivan; Maureira, Ignacio; Miranda-González, Nicolás; Barajas, Olga; Bustamante, Eva; Ahumada, Monica; Colombo, Alicia; Armisén, Ricardo; Villamán, Camilo; Ibañez, Carolina; Bravo, María L.; Sanhueza, Verónica; Spencer, Loreto; De Toro, Gonzalo; Morales, Erik; Bizama, Carolina; García, Patricia (2021)Next-generation sequencing (NGS) is progressively being used in clinical practice. However, several barriers preclude using this technology for precision oncology in most Latin American countries. To overcome some of these ...