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Computational analyses on genetic alterations in the NSD genes family and the implications for colorectal cancer development
D'Afonseca, Vívian; Gónzalez, Glória; Salazar, Marcela; Arencibia-Rodríguez, Ariel (2020)Colorectal cancer (CRC) is a prevalent tumour throughout the world. CRC symptoms appear only in advanced stages causing decrease in survival of patients. Therefore, it is necessary to establish new strategies to detect CRC ...
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Histone methyltransferases useful in gastric cancer research
Reyes, Dafne A.; Saure Sarría, Victor Manuel; Salazar, Marcela; D'Afonseca, Vívian (2021)Gastric cancer (GC) is one of the most frequent tumors in the world. Stomach adenocarcinoma is a heterogeneous tumor, turning the prognosis prediction and patients’ clinical management difficult. Some diagnosis tests for ...
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Identification of altered genes in gallbladder cancer as potential driver mutations for diagnostic and prognostic purposes: a computational approach
D'Afonseca, Vívian; Arencibia-Rodríguez, Ariel; Echeverría-Vega, Alex; Cerpa, Leslie; Cayún, Juan P.; Varela, Nelson M.; Salazar, Marcela; Quiñones, Luis A. (2020)Prognostic markers for cancer can assist in the evaluation of survival probability of patients and help clinicians to assess the available treatment modalities. Gallbladder cancer (GBC) is a rare tumor that causes 165 087 ...
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Simulation model for Hashimoto autoimmune thyroiditis disease
Salazar, Marcela; Vergaño-Salazar, J. G.; Pastenes, Luis; D'Afonseca, Vívian (2021)Hashimoto thyroiditis (HT) is a pathology that often causes a gradual thyroid insufficiency in affected patients due to the autoimmune destruction of this gland. The cellular immune response mediated by T helper lymphocytes ...