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The emerging role of the receptor for advanced glycation end products on innate immunity
| dc.contributor.author | Rojas, Armando | |
| dc.contributor.author | Pérez-Castro, Ramón | |
| dc.contributor.author | González-Bonet, Ileana | |
| dc.contributor.author | Delgado-López, Fernando | |
| dc.contributor.author | Romero, Jacqueline | |
| dc.contributor.author | Rojas, Israel | |
| dc.date.accessioned | 2017-11-03T20:20:46Z | |
| dc.date.available | 2017-11-03T20:20:46Z | |
| dc.date.issued | 2014 | |
| dc.identifier.uri | http://repositorio.ucm.cl/handle/ucm/1105 | |
| dc.description.abstract | Cells from innate immune system are activated by the engagement of germ-line encoded patternrecognition receptors (PRRs) in response to the microbial insult. These receptors are able to recognize either the presence of highly conserved microbial components called pathogen-associated molecular patterns or endogenous danger-associated molecular patterns. These danger signals are recognized by different types of (PRRs), including the receptor for advanced glycation end products. This new PRR share both ligands and intracellular signaling with Toll-like receptors and thus may cooperate with each other as essential partners to strength inflammatory response. This review summarizes recent advances in understanding the promiscuity of this receptor as well as its role in the context of innate immunity by triggering an inflammatory response when innate immune cells detect infection or tissue injury. | es_CL |
| dc.language.iso | en | es_CL |
| dc.rights | Atribución-NoComercial-SinDerivadas 3.0 Chile | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | * |
| dc.source | International Reviews of Immunology, 33, 67-80 | es_CL |
| dc.subject | Alarmins | es_CL |
| dc.subject | Danger-associated molecular patterns | es_CL |
| dc.subject | Innate immunity | es_CL |
| dc.subject | Pattern recognition receptors | es_CL |
| dc.subject | Receptor for advanced glycation end products | es_CL |
| dc.subject | Septic inflammation | es_CL |
| dc.title | The emerging role of the receptor for advanced glycation end products on innate immunity | es_CL |
| dc.type | Article | es_CL |
| dc.ucm.facultad | Facultad de Medicina | es_CL |
| dc.ucm.indexacion | Scopus | es_CL |
| dc.ucm.indexacion | Isi | es_CL |
| dc.ucm.uri | sibib2.ucm.cl:2048/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=mdc&AN=24266871&lang=es&site=eds-live&scope=site | es_CL |
| dc.ucm.doi | doi.org/10.3109/08830185.2013.849702 | es_CL |
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Excepto si se señala otra cosa, la licencia de la publicación se describe como Atribución-NoComercial-SinDerivadas 3.0 Chile