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dc.contributor.authorPalomo, Iván
dc.contributor.authorFuentes, Eduardo
dc.contributor.authorMoore-Carrasco, Rodrigo
dc.contributor.authorGonzález, Daniel R.
dc.contributor.authorRojas, Armando
dc.contributor.authorPadro, Teresa
dc.contributor.authorBadimon, Lina
dc.date.accessioned2017-12-13T12:47:57Z
dc.date.available2017-12-13T12:47:57Z
dc.date.issued2011
dc.identifier.urihttp://repositorio.ucm.cl/handle/ucm/1610
dc.description.abstractThe endothelium helps to maintain the normal structure and homeostasis of the vasculature. However, chronic exposure to cardiovascular (CV) risk factors causes endothelial dysfunction, a phenomenon that is characterized by inflammation, reduced bioavailability of nitric oxide (NO) and a prothrombotic state. Epidemiological studies have shown that regular consumption of fruits and vegetables reduces CV risk, which has caused interest in knowing the bioactive compounds and the mechanisms involved. Among the components that protect the endothelium are antioxidants (vitamin C, vitamin E and polyphenols) and polyunsaturated fatty acids. Vitamin C and E promote vasodilatation protecting NO by blocking the reactive oxygen species (ROS). Polyphenols improve endothelial function primarily by increasing levels of NO, and inhibition of angiogenesis and platelet activation. Diets rich in polyunsaturated fatty acids have shown beneficial effects by reducing the gene expression of cyclooxygenase-2 and the expression of cell adhesion molecules. This review mainly highlights the current understanding of endothelial dysfunction and the protective effect of endothelial cells by bioactive components of fruits and vegetables.es_CL
dc.language.isoeses_CL
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 Chile*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
dc.sourceRevista Chilena de Nutrición, 38(3), 343-355es_CL
dc.subjectCardiovascular diseaseses_CL
dc.subjectAtherosclerosises_CL
dc.subjectEndothelial dysfunctiones_CL
dc.subjectBiomarkerses_CL
dc.subjectFruites_CL
dc.subjectVegetableses_CL
dc.subjectPolyphenolses_CL
dc.titleEl consumo de frutas y hortalizas ayuda a prevenir el daño endoteliales_CL
dc.title.alternativeConsumption of fruits and vegetables in the prevention of endothelial damagees_CL
dc.typeArticlees_CL
dc.ucm.facultadFacultad de Medicinaes_CL
dc.ucm.indexacionScopuses_CL
dc.ucm.indexacionScieloes_CL
dc.ucm.doidx.doi.org/10.4067/S0717-75182011000300010es_CL


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Atribución-NoComercial-SinDerivadas 3.0 Chile
Excepto si se señala otra cosa, la licencia de la publicación se describe como Atribución-NoComercial-SinDerivadas 3.0 Chile