Background: Maximum oxygen consumption is an indicator of cardiorespiratory fitness. Aim: e purpose was, first, torelate and compare the VO2max as the dependent variable with the estimated distance in the six-minute walk test (SMWT)as the independent variable in university students and, secondly, to relate the distance (dependent) with demographic andanthropometric variables (independents). Methodology: A correlational, descriptive, and quantitative study with a non-experimental design was conducted on 110 university students. In the study, basic anthropometry and vital signs were measured.A direct method of VO2max (Bruce test) on a treadmill was applied. en, the distance covered in the SMWT was evaluated withtwo equations available in the scientific literature. Differences between men and women were measured in the tests, the correlationbetween the distances estimated with VO2max and anthropometric variables, and repeated ANOVA measurement tests betweenVO2max and estimated distance were analyzed with the SPSS v.22 program (p<0.05). Results: Significant correlations were foundbetween VO2max and estimated distances (p<0.05) in the total sample, men and women, and in some cases, the distance correlatedwith gender, age, weight, height, and BMI (p<0.05). However, there were differences between VO2max and distances estimatedin the SMWT (p<0.001). Conclusions: e VO2max measurement method is different from the distance prediction equations,although they have a significant relationship.