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Effects of resistance exercise training on redox homeostasis in older adults. A systematic review and meta-analysis

dc.contributor.authorCuyul-Vásquez, Iván
dc.contributor.authorBerríos-Contreras, Lily
dc.contributor.authorSoto-Fuentes, Stephanie
dc.contributor.authorHunter-Echeverría, Karina
dc.contributor.authorMarzuca-Nassr, Gabriel
dc.date.accessioned2023-04-18T15:00:55Z
dc.date.available2023-04-18T15:00:55Z
dc.date.issued2020
dc.identifier.urihttp://repositorio.ucm.cl/handle/ucm/4693
dc.description.abstractBackground: Resistance exercise training (RET) has proven effective at reducing the risk of chronic disease in older populations, and it appears to regulate redox homeostasis. Aims: To determine the effects of RET on redox homeostasis in older people. Study design: A systematic review and meta-analysis of randomized clinical trials identified by searching MEDLINE, Web of Science, EMBASE, Sportdiscus, LILACS, CENTRAL and CINAHL. We included studies of subjects aged 65 years or older, with or without pathologies, and including RET metrics with quantified molecular oxidation and antioxidant capacity outcomes. Results: Fifteen studies were included in this review. Agreement between reviewers reached a kappa value of 0.725. There were a total of 614 participants, with an average age of 68.1 years. Five (for molecular oxidation markers) and three (for antioxidant capacity markers) studies included data that quantified the effects of RET on homeostasis redox. The results of the meta-analysis showed that there were no differences in the molecular oxidation markers (SMD = −0.26; 95% CI = −0.57 to 0.05; P = 0.10; I2 = 0%) and antioxidant capacity markers (SMD = 0.53; 95% CI = −0.20 to 1.26; P = 0.16; I2 = 71.5%) in healthy older people after a RET of 8–24 weeks compared to non-intervention. Conclusions: Based on a small number of studies of low methodological quality, this systematic review with meta-analysis suggests that RET is not effective at reducing molecular oxidation markers in healthy older people. More research is needed on the effects of RET on redox homeostasis in older people.es_CL
dc.language.isoenes_CL
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 Chile*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
dc.sourceExperimental Gerontology, 138, 111012es_CL
dc.subjectResistance exercise traininges_CL
dc.subjectAntioxidantses_CL
dc.subjectOxidative stresses_CL
dc.subjectAginges_CL
dc.subjectExercisees_CL
dc.titleEffects of resistance exercise training on redox homeostasis in older adults. A systematic review and meta-analysises_CL
dc.typeArticlees_CL
dc.ucm.facultadFacultad de Ciencias de la Saludes_CL
dc.ucm.indexacionScopuses_CL
dc.ucm.indexacionIsies_CL
dc.ucm.urisibib2.ucm.cl:2048/login?url=https://www.sciencedirect.com/science/article/pii/S0531556520303600#:~:text=Resistance%20exercise%20training%20(RET)%20appears%20to%20regulate%20redox%20homeostasis.&text=We%20found%20no%20differences%20in,RET%20in%20healthy%20older%20people.&text=The%20redox%20homeostasis%20properties%20of%20RET%20in%20older%20people%20requires%20further%20researches_CL
dc.ucm.doidoi.org/10.1016/j.exger.2020.111012es_CL


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