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Fabrication of porous nano silica materials by template-assisted strategy for controlled drug delivery studies

dc.contributor.authorChirra, Suman
dc.contributor.authorReddy Gujjula, Sripal
dc.contributor.authorManda, Sathish
dc.contributor.authorGoskula, Srinath
dc.contributor.authorNarayanan, Venkatathri
dc.date.accessioned2025-07-04T17:51:25Z
dc.date.available2025-07-04T17:51:25Z
dc.date.issued2025
dc.identifier.urihttp://repositorio.ucm.cl/handle/ucm/6171
dc.description.abstractThe sol-gel method was employed to synthesize three-dimensional mesoporous Fe-KIT-6 and KIT-6. These materials were investigated for their potential in controlled drug delivery applications, with ibuprofen used as a model drug. Both Fe-KIT-6 and KIT-6 exhibit large pore volumes, narrow pore size distributions, and high surface areas, making them promising candidates for drug adsorption. The introduction of iron into the KIT-6 structure significantly enhanced its drug sorption capacity, with the materials showing an increased ability to adsorb ibuprofen as the iron content increased. Moreover, the release of ibuprofen was more efficient from iron-modified KIT-6, with materials containing iron exhibiting slower and more controlled drug release profiles. These results suggest that Fe-KIT-6 has potential for use in sustained-release drug delivery systems.es_CL
dc.language.isoenes_CL
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 Chile*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
dc.sourceJournal of Porous Materials, 32(2), 761-772es_CL
dc.subjectIbuprofenes_CL
dc.subjectDrug deliveryes_CL
dc.subjectAdsorptiones_CL
dc.subjectDesorptiones_CL
dc.subjectFe-KIT-6es_CL
dc.subjectKIT-6es_CL
dc.subjectMesoporous silicaes_CL
dc.subjectControlled releasees_CL
dc.titleFabrication of porous nano silica materials by template-assisted strategy for controlled drug delivery studieses_CL
dc.typeArticlees_CL
dc.ucm.indexacionScopuses_CL
dc.ucm.indexacionIsies_CL
dc.ucm.urispringerlink.ucm.elogim.com/article/10.1007/s10934-024-01735-0es_CL
dc.ucm.doidoi.org/10.1007/s10934-024-01735-0es_CL


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Atribución-NoComercial-SinDerivadas 3.0 Chile
Excepto si se señala otra cosa, la licencia de la publicación se describe como Atribución-NoComercial-SinDerivadas 3.0 Chile