Mostrar el registro sencillo de la publicación

dc.contributor.authorHuidobro-Muñoz, Andrea
dc.contributor.authorSilva-Prado, Raúl
dc.contributor.authorFerreccio, Catterina
dc.contributor.authorRoa, Juan Carlos
dc.contributor.authorBambs, Claudia
dc.contributor.authorVives, Alejandra
dc.contributor.authorCorvalán, Alejandro H.
dc.contributor.authorCortés, Sandra
dc.contributor.authorFoerster, Claudia
dc.contributor.authorAcevedo, Johanna
dc.contributor.authorPassi, Alvaro
dc.contributor.authorToro, Pablo
dc.contributor.authorCovacevich, Yerko
dc.contributor.authorDe la Cruz, Rolando
dc.contributor.authorKoshiol, Jill
dc.contributor.authorOlivares, Mauricio
dc.contributor.authorMiquel, Juan Francisco
dc.contributor.authorCruz, Francisco
dc.contributor.authorQuest, Andrew F.
dc.contributor.authorKogan, Marcelo J.
dc.contributor.authorCastro, Pablo F.
dc.contributor.authorLavandero, Sergio
dc.date.accessioned2017-10-18T12:54:21Z
dc.date.available2017-10-18T12:54:21Z
dc.date.issued2016
dc.identifier.urihttp://repositorio.ucm.cl/handle/ucm/667
dc.description.abstractBackground: Maule Cohort (MAUCO), a Chilean cohort study, seeks to analyze the natural history of chronic diseases in the agricultural county of Molina (40,000 inhabitants) in the Maule Region, Chile. Molina´s population is of particular interest because in the last few decades it changed from being undernourished to suffering excess caloric intake, and it currently has the highest national rates of cardiovascular diseases, stomach cancer and gallbladder cancer. Between 2009 and 2011 Molina´s poverty rate dropped from 24.1 % to 13.5 % (national average 20.4 %); in this period the county went from insufficient to almost complete basic sanitation. Despite these advances, chemical pollutants in the food and air are increasing. Thus, in Molina risk factors typical of both under-developed and developed countries coexist, generating a unique profile associated with inflammation, oxidative stress and chronic diseases. Methods/Design: MAUCO is the core project of the recently established Advanced Center for Chronic Diseases (ACCDiS), Universidad de Chile & Pontificia Universidad Católica de Chile. In this study, we are enrolling and following 10,000 adults aged 38 to 74 years over 10 years. All eligible Molina residents will be enrolled. Participants were identified through a household census. Consenting individuals answer an epidemiological survey exploring risk factors (psycho-social, pesticides, diet, alcohol, and physical activity), medical history and physical and cognitive conditions; provide fasting blood, urine, and saliva samples; receive an electrocardiogram, abdominal ultrasound and bio-impedance test; and take a hand-grip strength test. These subjects will be re-interviewed after 2, 5 and 7 years. Active surveillance of health events is in place throughout the regional healthcare system. The MAUCO Bio-Bank will store 30 to 50 aliquots per subject using an NIH/NCI biorepository system for secure and anonymous linkage of samples with data. Discussion: MAUCO´s results will help design public health interventions tailored to agricultural populations in Latin America.es_CL
dc.language.isoenes_CL
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 Chile*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
dc.sourceBMC Public Health, 16, 122es_CL
dc.subjectProspective studieses_CL
dc.subjectCohort studieses_CL
dc.subjectPopulation surveillancees_CL
dc.subjectChronic disease/epidemiologyes_CL
dc.subjectAgricultural workers diseaseses_CL
dc.subjectCardiovascular diseaseses_CL
dc.subjectNeoplasms/Epidemiologyes_CL
dc.titleStudy protocol for the Maule Cohort (MAUCO) of chronic diseases, Chile 2014–2024es_CL
dc.typeArticlees_CL
dc.ucm.facultadFacultad de Medicinaes_CL
dc.ucm.indexacionScopuses_CL
dc.ucm.indexacionIsies_CL
dc.ucm.doidoi.org/10.1186/s12889-015-2454-2es_CL


Ficheros en la publicación

Thumbnail
Vista Previa No Disponible

Esta publicación aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo de la publicación

Atribución-NoComercial-SinDerivadas 3.0 Chile
Excepto si se señala otra cosa, la licencia de la publicación se describe como Atribución-NoComercial-SinDerivadas 3.0 Chile