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The bisphosphonate zoledronic acid is a TRPV1 channel inhibitor
Castillo, Karen; Duarte, Yorley; Segura, Ignacio A.; Tricarico, Domenico; Chavez, Andres; Latorre, Ramón; Meza, Rodrigo; Ancaten, Carlos; Carvajal-Zamorano, Karina; Scala, Rosa (2023)The heat and capsaicin sensor, the transient receptor potential vanilloid type 1 (TRPV1) channel, is critically involved in pain sensation. Using compounds that activate TRPV1, such as capsaicin (CAP), produces analgesic ...