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Design, synthesis and in vitro cytotoxic evaluation of β-carboline tethered quinoline-4-carboxamide conjugates as DNA-interactive Topo II inhibitors
Prakash Soni, Jay; Devi, Priyanka; Chemitikanti, Sowjanya; Sharma, Anamika; Dinesh Swamy, Chintha Venkata; Phanindranath, Regur; Sathish, Manda; Nagesh, Narayana; Godugu, Chandraiah; Shankaraiah, Nagula (2023)In a pursuit for effective anticancer hit/lead, a series of new β-carboline tethered quinoline-4-carboxamides, adjoining noticeable pharmacophoric properties, were synthesized. The in vitro cytotoxicity evaluation established ...