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Mostrando publicaciones 1-6 de 6
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HMGB1 decreases CCR-2 expression and migration of M2 macrophages under hypoxia
Araya, Paulina; Romero, Jacqueline; Delgado-López, Fernando; Gonzalez, Ileana; Añazco-Oyarzún, Carolina; Perez, Ramón; Rojas, Armando (2019)Objective: The hypoxic milieu at tumor microenvironment is able to drive the behavior of infiltrating tumor cells. Considering that hypoxia-mediated HMGB1 release is known to promote tumor growth, as well to enhance the ...
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Pattern recognition receptors and their roles in the host response to helicobacter pylori infection
Gonzalez, Ileana; Araya, Paulina; Schneider, Iván; Lindner-Sanhueza, Cristian; Rojas, Armando (2021)Helicobacter pylori (H. pylori) infection is highly prevalent, affecting 4.4 billion people globally. This pathogen is a risk factor in the pathogenesis of more than 75% of worldwide cases of gastric cancer. Pattern ...
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Polyphenols and AGEs/RAGE axis. Trends and challenges
The formation of advanced glycation end-products (AGEs) is a key pathophysiological event linked not only to the onset and progression of diabetic complications, but also to neurodegeneration, cardiovascular diseases, ...
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RID: evaluation of the possible inhibiting effect of the proinflammatory signaling induced by TNF-α through NF-κβ and AP-1 in two cell lines of breast cancer
Monsalve, Francisco A.; Rojas, Armando ; Gonzalez, Ileana; Perez, Ramón; Añasco, Carolina; Romero, Jacqueline; Araya, Paulina; Santos, Leonardo S.; Delgado-López, Fernando (2020)Receptor internalization and degradation (RID), is a transmembrane protein coded within the E3 region expression cassette of adenoviruses. RID downregulates the cell surface expression of epidermal growth factor receptor ...
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Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) infection in household contacts and related factors during the first and second waves of the COVID-19 pandemic in Chile: a longitudinal cohort study
Urquidi, Cinthya; Rebolledo, Victor; Chaparro, Alejandra; Gonzalez, Ileana; Delgado, Fernando; Realini, Ornella; Valenzuela, Maria Teresa; Ventura, Maximiliano; Brizuela, Claudia; Reyes-López, Felipe; Sandino, Ana (2023)Background: Households are the high-risk setting for SARS-CoV-2 transmission, especially for close and prolonged person-to-person contact. However, the role of household structural and clinical factors, especially ...