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HMGB1 decreases CCR-2 expression and migration of M2 macrophages under hypoxia
Araya, Paulina; Romero, Jacqueline; Delgado-López, Fernando; Gonzalez, Ileana; Añazco-Oyarzún, Carolina; Perez, Ramón; Rojas, Armando (2019)Objective: The hypoxic milieu at tumor microenvironment is able to drive the behavior of infiltrating tumor cells. Considering that hypoxia-mediated HMGB1 release is known to promote tumor growth, as well to enhance the ...
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RID: evaluation of the possible inhibiting effect of the proinflammatory signaling induced by TNF-α through NF-κβ and AP-1 in two cell lines of breast cancer
Monsalve, Francisco A.; Rojas, Armando ; Gonzalez, Ileana; Perez, Ramón; Añasco, Carolina; Romero, Jacqueline; Araya, Paulina; Santos, Leonardo S.; Delgado-López, Fernando (2020)Receptor internalization and degradation (RID), is a transmembrane protein coded within the E3 region expression cassette of adenoviruses. RID downregulates the cell surface expression of epidermal growth factor receptor ...