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Extended batch cultures for poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) production by azotobacter vinelandii OP growing at different aeration rates
Urtuvia, Viviana; Ponce, Belén; Andler-Osorio, Rodrigo; Peña-Varas, Carlos; Diaz-Barrera, Alvaro (2022)Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) is a polymer produced by Azotobacter vinelandii OP. In the bioreactor, PHBV production and its molar composition are affected by aeration rate. PHBV production by A. ...
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Iridoid esters from Valeriana pavonii Poepp. & Endl. as GABAA modulators: structural insights in their binding mode and structure-activity relationship
Giraldo, Sara E.; Bedoya, Mauricio; Peña-Varas, Carlos; Santana, Paula A; Bazzocchi, Isabel L.; Jiménez, Ignacio A.; Marder, Mariel; Vergel, Nadezdha E.; Guerrero, Mario F.; Ramírez, David (2023)Context: Valeriana pavonii Poepp. & Endl. (Caprifoliaceae), is a plant used in traditional medicine as a tranquilizer in Colombia. Valerian extracts have been widely used since ancient times for their sedative and anxiolytic ...
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New drug design avenues targeting alzheimer’s disease by pharmacoinformatics-aided tools
Arrué, Lily; Cigna-Méndez, Alexandra; Barbosa, Tábata; Borrego-Muñoz, Paola; Struve-Villalobos, Silvia; Oviedo, Victoria; Martínez-García, Claudia; Sepúlveda-Lara, Alexis; Millán, Natalia; Márquez Montesinos, José C. E; Muñoz, Juana; Santana, Paula A; Peña-Varas, Carlos; Barreto, George E; González, Janneth; Ramírez, David; Arrué (2022)Neurodegenerative diseases (NDD) have been of great interest to scientists for a long time due to their multifactorial character. Among these pathologies, Alzheimer’s disease (AD) is of special relevance, and despite the ...