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Mostrando publicaciones 1-3 de 3
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Deletion of hippocampal Glucocorticoid receptors unveils sex-biased microRNA expression and neuronal morphology alterations in mice
Tejos-Bravo, Macarena; Oakley, Robert H.; Whirledge, Shannon D.; Corrales, Wladimir; Silva, Juan P.; García-Rojo, Gonzalo; Toledo, Jorge; Sanchez, Wendy; Román-Albasini, Luciano; Aliaga-Rojas, Esteban; Aguayo, Felipe; Olave, Felipe A.; Marcaja-Coutinho, Vinicius; Cidlowski, John A.; Fiedler, Jenny L. (2021)Sex differences in the brain have prompted many researchers to investigate the underlying molecular actors, such as the glucocorticoid receptor (GR). This nuclear receptor controls gene expression, including microRNAs ...
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MicroRNA profiling and bioinformatics target analysis in dorsal hippocampus of chronically stressed rats: Relevance to depression pathophysiology
Muñoz-Llanos, Mauricio; García-Pérez, María A.; Xu, Xiaojiang; Tejos-Bravo, Macarena; Vidal, Elena A.; Moyano, Tomás C.; Gutiérrez, Rodrigo A.; Aguayo, Felipe I.; Pacheco, Aníbal; García-Rojo, Gonzalo; Aliaga-Rojas, Esteban; Rojas, Paulina S.; Cidlowski, John A.; Fiedler, Jenny L. (2018)Studies conducted in rodents subjected to chronic stress and some observations in humans after psychosocial stress, have allowed to establish a link between stress and the susceptibility to many complex diseases, including ...
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Sex-dependent changes of miRNA levels in the hippocampus of adrenalectomized rats following acute corticosterone administration
Corrales, Wladimir; Silva, Juan P.; Parra, Claudio S.; Olave, Felipe A.; Aguayo, Felipe; Román-Albasini, Luciano; Aliaga-Rojas, Esteban; Venegas-Zamora, Leslye; Avalos, Ana M.; Rojas, P.S.; Marcaja-Coutinho, Vinicius; Oakley, Robert H.; Cidlowski, John A.; Fiedler, Jenny L. (2021)We explored sex-biased effects of the primary stress glucocorticoid hormone corticosterone on the miRNA expression profile in the rat hippocampus. Adult adrenalectomized (ADX) female and male rats received a single ...