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Decreased phosphorylation of Y14Caveolin-1 in endometrial tissue of polycystic ovary syndrome patients may be related with an insulin resistant state in this tissue
Ormazabal-Leiva, Paulina; Romero, C.; Gabler, F.; Quest, Andrew F.; Vega, M. (2013)Endometrial tissue of patients with polycystic ovary syndrome (PCOS) shows an impaired expression of insulin signaling molecules. Tyrosine phosphorylation of the insulin receptor (IR) by insulin promotes glucose uptake by ...
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Testosterone modulates the expression of molecules linked to insulin action and glucose uptake in endometrial cells
Ormazabal-Leiva, Paulina; Romero, C.; Quest, Andrew F.; Vega, M. (2013)Polycystic ovary syndrome (PCOS) is a common hyperandrogenic disorder associated with insulin resistance. Insulin exerts its metabolic function by activating the PI3K/Akt pathway and favoring glucose uptake. Caveolin-1 is ...