• Cohort profile: The Maule Cohort (MAUCO) 

    Ferreccio, Catterina; Huidobro-Muñoz, Andrea; Cortés, Sandra; Bambs, Claudia; Toro, Pablo; Van de Wyngard, Vanessa; Acevedo, Johanna; Paredes, Fabio; Venegas, Pia; Verdejo, Hugo E.; Oyarzún-González, Ximena; Cook, Paz; Castro, Pablo F.; Foerster, Claudia; Vargas, Claudio; Koshiol, Jill; Araya, Juan C.; Cruz, Francisco; Corvalán, Alejandro H.; Quest, Andrew F.; Kogan, Marcelo J.; Lavandero, Sergio (2020)
  • Decreased phosphorylation of Y14Caveolin-1 in endometrial tissue of polycystic ovary syndrome patients may be related with an insulin resistant state in this tissue 

    Ormazabal-Leiva, Paulina; Romero, C.; Gabler, F.; Quest, Andrew F.; Vega, M. (2013)
    Endometrial tissue of patients with polycystic ovary syndrome (PCOS) shows an impaired expression of insulin signaling molecules. Tyrosine phosphorylation of the insulin receptor (IR) by insulin promotes glucose uptake by ...

  • Study protocol for the Maule Cohort (MAUCO) of chronic diseases, Chile 2014–2024 

    Huidobro-Muñoz, Andrea; Silva-Prado, Raúl; Ferreccio, Catterina; Roa, Juan Carlos; Bambs, Claudia; Vives, Alejandra; Corvalán, Alejandro H.; Cortés, Sandra; Foerster, Claudia; Acevedo, Johanna; Passi, Alvaro; Toro, Pablo; Covacevich, Yerko; De la Cruz, Rolando; Koshiol, Jill; Olivares, Mauricio; Miquel, Juan Francisco; Cruz, Francisco; Quest, Andrew F.; Kogan, Marcelo J.; Castro, Pablo F.; Lavandero, Sergio (2016)
    Background: Maule Cohort (MAUCO), a Chilean cohort study, seeks to analyze the natural history of chronic diseases in the agricultural county of Molina (40,000 inhabitants) in the Maule Region, Chile. Molina´s population ...

  • Testosterone modulates the expression of molecules linked to insulin action and glucose uptake in endometrial cells 

    Ormazabal-Leiva, Paulina; Romero, C.; Quest, Andrew F.; Vega, M. (2013)
    Polycystic ovary syndrome (PCOS) is a common hyperandrogenic disorder associated with insulin resistance. Insulin exerts its metabolic function by activating the PI3K/Akt pathway and favoring glucose uptake. Caveolin-1 is ...