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Structure/activity analysis of TASK-3 channel antagonists based on a 5,6,7,8 tetrahydropyrido[4,3-d]pyrimidine
Ramírez, David; Bedoya, Mauricio; Kiper, Aytug K.; Rinné, Susanne; Morales-Navarro, Samuel; Hernández-Rodríguez, Erix W.; Sepúlveda, Francisco V.; Drecher, Niels; González, Wendy (2019)TASK-3 potassium (K+) channels are highly expressed in the central nervous system, regulating the membrane potential of excitable cells. TASK-3 is involved in neurotransmitter action and has been identified as an oncogenic ...