Listar por autor
Mostrando publicaciones 1-12 de 12
-
Alzheimer's disease susceptibility gene Apolipoprotein E (APOE) and blood biomarkers in UK Biobank (N = 395,769)
Ferguson, Amy C.; Tank, Rachana; Lyall, Laura M.; Ward, Joey; Celis-Morales, Carlos; Strawbridge, Rona; Ho, Frederick; Whelan, Christopher D.; Gill, Jason M.R.; Welsh, Paul; Anderson, Jana J.; Mark, Patrick B.; Mackay, Daniel; Smith, Daniel J.; Pell, J.P.; Cavanagh, Jonathan; Sattar, Naveed; Lyall, Donald (2020)Background: Alzheimer's disease (AD) is a neurodegenerative condition where the underlying etiology is still unclear. Investigating the potential influence of apolipoprotein E (APOE), a major genetic risk factor, on common ...
-
Are people with metabolically healthy obesity really healthy? A prospective cohort study of 381,363 UK Biobank participants
Zhou, Ziyi; Macpherson, John; Gray, S.R.; Gill, Jason M.R.; Welsh, Paul; Celis-Morales, Carlos; Sattar, Naveed; Pell, J.P.; Ho, Frederick (2021)Aims/hypothesis: People with obesity and a normal metabolic profile are sometimes referred to as having ‘metabolically healthy obesity’ (MHO). However, whether this group of individuals are actually ‘healthy’ is uncertain. ...
-
Association between device-measured physical activity and incident heart failure: a prospective cohort study of 94 739 uk biobank participants
Ho, Frederick; Zhou, Ziyi; Petermann-Rocha, Fanny; Para-Soto, Solange; Boonpor, Jirapitcha; Welsh, Paul; Gill, Jason M.R.; Gray, S.R.; Sattar, Naveed; Pell, J.P.; Celis-Morales, Carlos (2022)Background: Studies of objectively measured physical activity (PA) have investigated acute cardiovascular outcomes but not heart failure (HF), an emerging chronic condition. This study aimed to investigate the dose-response ...
-
Associations and predictive performance of 11 anthropometric measures with incident type 2 diabetes: a prospective cohort study from the UK Biobank
Boonpor, Jirapitcha; Parra‑Soto, Solange; Talebi, Atefeh; Zhou, Ziyi; Carrasco-Marin, Fernanda; Petermann-Rocha, Fanny; Welsh, Paul; Pell, J.P.; Sattar, Naveed; Gill, Jason M.R.; Gray, S.R.; Celis-Morales, Carlos; Ho, Frederick (2023)Objective The study aim was to investigate associations of 11 anthropometric measures with incident type 2 diabetes and compare their predictive performance. Methods This prospective cohort study included 161,127 White ...
-
Associations between grip strength and incident type 2 diabetes: findings from the UK Biobank prospective cohort study
Boonpor, Jirapitcha; Parra, Solange; Petermann-Rocha, Fanny; Ferrari, Gerson Luis de Moraes; Welsh, Paul; Pell, J.P.; Sattar, Naveed; Gill, Jason M.R.; Ho, Frederick; Gray, S.R.; Celis-Morales, Carlos (2021)Introduction: Grip strength has been associated with chronic diseases and mortality. However, current evidence of the association between grip strength and incident type 2 diabetes mellitus (T2DM) is controversial. The aim ...
-
Associations of fat and carbohydrate intake with cardiovascular disease and mortality: prospective cohort study of UK Biobank participants
Ho, Frederick; Gray, S.R.; Welsh, Paul; Petermann-Rocha, Fanny; Foster, Hamish M. E.; Waddell, Heather; Anderson, Jana J.; Lyall, Donald; Sattar, Naveed; Gill, Jason M.R.; Mathers, John; Pell, J.P.; Celis-Morales, Carlos (2020)Objective: To investigate the association of macronutrient intake with all cause mortality and cardiovascular disease (CVD), and the implications for dietary advice. Design: Prospective population based study. Setting: ...
-
Comparison of two different frailty measurements and risk of hospitalisation or death from COVID-19: findings from UK Biobank
Petermann-Rocha, Fanny; Hanlon, Peter; Gray, S.R.; Welsh, Paul; Gill, Jason M.R.; Foster, Hamish M. E.; Katikireddi, Vittal S.; Lyall, Donald; Mackay, Daniel; O’Donnell, Catherine A.; Sattar, Naveed; Nicholl, Barbara I.; Pell, J.P.; Jani, Bhautesh D.; Ho, Frederick; Mair, Frances S.; Celis-Morales, Carlos (2020)Background. Frailty has been associated with worse prognosis following COVID-19 infection. While several studies have reported the association between frailty and COVID-19 mortality or length of hospital stay, there have ...
-
Dose–response relationship between device-measured physical activity and incident type 2 diabetes: findings from the UK Biobank prospective cohort study
Boonpor, Jirapitcha; Parra‑Soto, Solange; Petermann-Rocha, Fanny; Lynskey, Nathan; Cabanas-Sánchez, Verónica; Sattar, Naveed; Gill, Jason M.R.; Welsh, Paul; Pell, J.P.; Gray, S.R.; Ho, Frederick; Celis-Morales, Carlos (2023)Background Most studies investigating the association between physical activity (PA) and the risk of type 2 diabetes are derived from self-reported questionnaires, with limited evidence using device-based measurements. ...
-
Identifying the biomarker profile of pre-frail and frail people: a cross-sectional analysis from UK biobank
Chu, Wenying; Lynskey, Nathan; Iain-Ross, James; Pell, J.P.; Sattar, Naveed; Ho, Frederick; Welsh, Paul; Celis-Morales, Carlos; Petermann-Rocha, Fanny (2023)Objective: This study aimed to compare the biomarker profile of pre-frail and frail adults in the UK Biobank cohort by sex. Methods: In total, 202,537 participants (67.8% women, aged 37 to 73 years) were included in this ...
-
Physical capability markers used to define sarcopenia and their association with cardiovascular and respiratory outcomes and all-cause mortality: a prospective study from UK biobank
Petermann-Rocha, Fanny; Ho, Frederick; Welsh, Paul; Mackay, Daniel; Brown, Rosemary E.; Gill, Jason M.R.; Sattar, Naveed; Gray, S.R.; Pell, J.P.; Celis-Morales, Carlos (2020)Introduction: It is unclear what combinations of physical capability markers used to define sarcopenia have the strongest associations with health outcomes. Aim: To compare the associations between different combinations ...
-
Understanding how much TV is too much: a nonlinear analysis of the association between television viewing time and adverse health outcomes
Foster, Hamish M. E.; Ho, Frederick; Sattar, Naveed; Welsh, Paul; Pell, J.P.; Gill, Jason M.R.; Gray, S.R.; Celis-Morales, Carlos (2020)Objective: To inform potential guideline development, we investigated nonlinear associations between television viewing time (TV time) and adverse health outcomes. Methods: From 2006 to 2010, 490,966 UK Biobank participants, ...
-
Vegetarians, fish, poultry, and meat-eaters: Who has higher risk of cardiovascular disease incidence and mortality? A prospective study from UK Biobank
Petermann-Rocha, Fanny; Parra, Solange; Gray, S.R.; Anderson, Jana J.; Welsh, Paul; Gill, Jason M.R.; Ho, Frederick; Celis-Morales, Carlos; Pell, J.P.; Sattar, Naveed (2021)Aims: To compare the incidence and mortality risk for cardiovascular diseases (CVD) [CVD and also ischaemic heart disease (IHD), myocardial infarction (MI), stroke, and heart failure (HF)] among people with different types ...