• Epigenome-wide analysis of methylation changes in the sequence of gallstone disease, dysplasia, and gallbladder cancer 

    Brägelmann, Johannes; Barahona-Ponce, Carol; Marcelain, Katherine; Roessler, Stephanie; Goeppert, Benjamin; Gallegos, Ivan; Colombo, Alicia; Sanhueza, Verónica; Morales, Erik; Rivera, María T.; De Toro, Gonzalo; Ortega, Alejandro; Müller, Bettina; Gabler, F.; Scherer, Dominique; Waldenberger, Melanie; Reischl, Eva; Boekstegers, Felix; Garate-Calderon, Valentina; Umu, Sinan U.; Rounge, Trine B.; Popanda, Odilia; Lorenzo-Bermejo, Justo (2021)
    Background and Aims: Gallbladder cancer (GBC) is a highly aggressive malignancy of the biliary tract. Most cases of GBC are diagnosed in low-income and middle-income countries, and research into this disease has long been ...

  • Validation of an NGS panel designed for detection of actionable mutations in tumors common in Latin America 

    Salvo, Mauricio; González-Feliú, Evelin; Toro, Jessica; Gallegos, Ivan; Maureira, Ignacio; Miranda-González, Nicolás; Barajas, Olga; Bustamante, Eva; Ahumada, Monica; Colombo, Alicia; Armisén, Ricardo; Villamán, Camilo; Ibañez, Carolina; Bravo, María L.; Sanhueza, Verónica; Spencer, Loreto; De Toro, Gonzalo; Morales, Erik; Bizama, Carolina; García, Patricia (2021)
    Next-generation sequencing (NGS) is progressively being used in clinical practice. However, several barriers preclude using this technology for precision oncology in most Latin American countries. To overcome some of these ...