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Are the effects of DES over? a tragic lesson from the past
Zamora-León, Pilar (2021)Diethylstilbestrol (DES), a transplacental endocrine-disrupting chemical, was prescribed to pregnant women for several decades. The number of women who took DES is hard to know precisely, but it has been estimated that ...
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Breast cancer and environmental contamination: A real connection?
Delgado-López, Fernando; Zamora-León, Pilar (2018)Breast cancer is the most prevalent cancer among women and the second cause of cancer-related death in the world. This review describes the effects of bisphenol A, phthalates, and parabens, important environmental chemicals ...
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Cytotoxic effect of geranylphenol derivatives in the human breast cancer cell line MDA-MB-231 and gastric cancer cell line MKN74
Espinoza, Luis; Taborga, Lautaro; Araya, Paulina; Delgado-López, Fernando; Zamora-León, Pilar (2020)Background: Previous studies have demonstrated that geranyl metabolites, found mainly in marine organisms, exhibit interesting antimicrobial and antifungal activities. In addition, linear geranyl derivatives have been ...
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Polycyclic Aromatic Hydrocarbons and their Association with Breast Cancer
Zamora-León, Pilar; Delgado-López, Fernando (2020)Background and Rationale: Polycyclic aromatic hydrocarbons are a lipophilic group of pollutants that persist in the atmosphere for long periods, constituting a permanent source of exposure for humans. They have been ...
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Selegiline (deprenyl) decreases calbindin-D28k expression in cortical neurons of rats socially deprived during the post-weaning period
Pascual, Rodrigo; Zamora-León, Pilar; Bustamante, Carlos (2013)Preclinical studies indicate that selegiline (deprenyl), frequently used in some neurodegenerative diseases, exert protective effects on central nervous system neurons ofindividuals exposed to social isolation (SI). ...