• Main methods and tools for peptide development based on protein-protein interactions (PPIs) 

    Baeza, Javiera; Bedoya, Mauricio; Cruz, Pablo; Ojeda, Paola; Adasme-Carreño, Francisco; Cerda, Oscar; González, Wendy (2025)
    Protein-protein interactions (PPIs) regulate essential physiological and pathological processes. Due to their large and shallow binding surfaces, PPIs are often considered challenging drug targets for small molecules. ...

  • Pharmaceutical applications of cyclotides 

    Ojeda, Paola G.; Cardoso, Marlon H.; Franco, Octávio L. (2019)
    Cyclotides are cyclic peptides, present in several plant families, that show diverse biological properties. Structurally, cyclotides share a distinctive head-to-tail circular knotted topology of three disulfide bonds. This ...