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The emerging therapeutic potential of nitro fatty acids and other michael acceptor-containing drugs for the treatment of inflammation and cancer
Piesche, Matthias; Roos, Jessica; Kühn, Benjamin; Fettel, Jasmin; Hellmuth, Nadine; Brat, Camilla; Maucher, Isabelle V.; Awad, Omar; Matrone, Carmela; Comerma-Steffensen, Simon G.; Manolikakes, Georg; Heinicke, Ulrike; Zacharowski, Kai D.; Steinhilber, Dieter; Maier, Thorsten J. (2020)Nitro fatty acids (NFAs) are endogenously generated lipid mediators deriving from reactions of unsaturated electrophilic fatty acids with reactive nitrogen species. Furthermore, Mediterranean diets can be a source of NFA. ...