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The ROCK inhibitor fasudil prevents chronic restraint stress-induced depressive-like behaviors and dendritic spine loss in rat hippocampus
Aliaga-Rojas, Esteban; García-Rojo, Gonzalo; Fresno, Cristóbal; Vilches, Natalia; Mora, Sergio; Tejos, Macarena; Díaz-Véliz, Gabriela; Aguayo, Felipe I.; Fiedler, Jenny L.; Parra, Claudio S.; Parra-Fiedler, Nicolás; Rojas, Paulina S.; Pacheco, Aníbal (2017)Background: Dendritic arbor simplification and dendritic spine loss in the hippocampus, a limbic structure implicated in mood disorders, are assumed to contribute to symptoms of depression. These morphological changes imply ...