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Genistein activates transcription factor EB and corrects Niemann–Pick C phenotype
Argüello-Florencio, Graciela R.; Balboa, Elisa; Castro, Juan; Yañez, María José; Mattar, Pamela; Pulgar, Rodrigo; Zanlungo, Silvana; Tapia, Pablo J. (2021)Niemann–Pick type C disease (NPCD) is a lysosomal storage disease (LSD) characterized by abnormal cholesterol accumulation in lysosomes, impaired autophagy flux, and lysosomal dysfunction. The activation of transcription ...