Listar por materia "Apoptosis"
Mostrando publicaciones 1-3 de 3
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Design, synthesis and in vitro cytotoxic evaluation of β-carboline tethered quinoline-4-carboxamide conjugates as DNA-interactive Topo II inhibitors
(2023)In a pursuit for effective anticancer hit/lead, a series of new β-carboline tethered quinoline-4-carboxamides, adjoining noticeable pharmacophoric properties, were synthesized. The in vitro cytotoxicity evaluation established ...
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In Vivo and in vitro antitumor activity of tomatine in hepatocellular carcinoma
(2022)Background: There is abundant ethnopharmacological evidence the uses of regarding Solanum species as antitumor and anticancer agents. Glycoalkaloids are among the molecules with antiproliferative activity reported in these ...
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Pro-resolving lipid mediator resolvin E1 mitigates the progress of diethylnitrosamine-induced liver fibrosis in sprague-dawley rats by attenuating fibrogenesis and restricting proliferation
(2020)Liver fibrosis is a complex process associated to most types of chronic liver disease, which is characterized by a disturbance of hepatic tissue architecture and the excessive accumulation of extracellular matrix. Resolvin ...