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Listar por materia "Cholesterol"

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  • A positive relationship between exposure to heavy metals and development of chronic diseases: A case study from Chile 

    Cortés, Sandra; Zúñiga-Venegas, Liliana A.; Pancetti, Floria; Covarrubias, Alejandra; Ramírez-Santana, Muriel; Adaros, Héctor; Muñoz, Luis (2021)
    Chile is a mining country, where waste mining is frequently found in the vicinity of inhabited areas. To explore the association between metal exposure and alterations in glucose metabolism, inflammatory status, and oxidative ...

  • Alzheimer's disease susceptibility gene Apolipoprotein E (APOE) and blood biomarkers in UK Biobank (N = 395,769) 

    Ferguson, Amy C.; Tank, Rachana; Lyall, Laura M.; Ward, Joey; Celis-Morales, Carlos; Strawbridge, Rona; Ho, Frederick; Whelan, Christopher D.; Gill, Jason M.R.; Welsh, Paul; Anderson, Jana J.; Mark, Patrick B.; Mackay, Daniel; Smith, Daniel J.; Pell, J.P.; Cavanagh, Jonathan; Sattar, Naveed; Lyall, Donald (2020)
    Background: Alzheimer's disease (AD) is a neurodegenerative condition where the underlying etiology is still unclear. Investigating the potential influence of apolipoprotein E (APOE), a major genetic risk factor, on common ...

  • Effect of exogenous lipids on cryotolerance of atlantic salmon (salmo salar) spermatozoa 

    Díaz, Rommy; Quiñones, John; Short, Stefania; Contreras, Pablo; Ulloa-Rodríguez, Patricio; Cancino-Baier, David; Sepúlveda, Néstor; Valdebenito, Iván; Farías, Jorge G. (2021)
    The development of semen cryopreservation strategies is necessary to improve the semen storage technologies of species of great commercial interest for aquaculture. Recent studies demonstrate that lipids play an important ...

  • Genistein activates transcription factor EB and corrects Niemann–Pick C phenotype 

    Argüello-Florencio, Graciela R.; Balboa, Elisa; Castro, Juan; Yañez, María José; Mattar, Pamela; Pulgar, Rodrigo; Zanlungo, Silvana; Tapia, Pablo J. (2021)
    Niemann–Pick type C disease (NPCD) is a lysosomal storage disease (LSD) characterized by abnormal cholesterol accumulation in lysosomes, impaired autophagy flux, and lysosomal dysfunction. The activation of transcription ...