Listar por materia "Cytotoxicity"
Mostrando publicaciones 1-2 de 2
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Cytotoxic effect of geranylphenol derivatives in the human breast cancer cell line MDA-MB-231 and gastric cancer cell line MKN74
(2020)Background: Previous studies have demonstrated that geranyl metabolites, found mainly in marine organisms, exhibit interesting antimicrobial and antifungal activities. In addition, linear geranyl derivatives have been ...
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Design, synthesis and in vitro cytotoxic evaluation of β-carboline tethered quinoline-4-carboxamide conjugates as DNA-interactive Topo II inhibitors
(2023)In a pursuit for effective anticancer hit/lead, a series of new β-carboline tethered quinoline-4-carboxamides, adjoining noticeable pharmacophoric properties, were synthesized. The in vitro cytotoxicity evaluation established ...