Listar por materia 

Listar por materia "Dendritic spines"

Mostrando publicaciones 1-4 de 4

  • A centronuclear myopathy-causing mutation in dynamin-2 disrupts neuronal morphology and excitatory synaptic transmission in a murine model of the disease 

    Arriagada-Diaz, Jorge; Flores-Muñoz, Carolina; Gomez-Soto, Bárbara; Labraña-Allende, Marjorie; Mattar-Araos, Michelle; Prado-Vega, Lorena; Hinostroza, Fernando; Gajardo, Ivana; Guerra-Fernández, María José; Bevilacqua, Jorge A.; Cárdenas, Ana M.; Bitoun, Marc; Ardiles, Alvaro O.; Gonzalez-Jamett, Arlek M. (2023)
    Aims Dynamin-2 is a large GTPase, a member of the dynamin superfamily that regulates membrane remodelling and cytoskeleton dynamics. Mutations in the dynamin-2 gene (DNM2) cause autosomal dominant centronuclear myopathy ...

  • Deletion of hippocampal Glucocorticoid receptors unveils sex-biased microRNA expression and neuronal morphology alterations in mice 

    Tejos-Bravo, Macarena; Oakley, Robert H.; Whirledge, Shannon D.; Corrales, Wladimir; Silva, Juan P.; García-Rojo, Gonzalo; Toledo, Jorge; Sanchez, Wendy; Román-Albasini, Luciano; Aliaga-Rojas, Esteban; Aguayo, Felipe; Olave, Felipe A.; Marcaja-Coutinho, Vinicius; Cidlowski, John A.; Fiedler, Jenny L. (2021)
    Sex differences in the brain have prompted many researchers to investigate the underlying molecular actors, such as the glucocorticoid receptor (GR). This nuclear receptor controls gene expression, including microRNAs ...

  • Hippocampal memory recovery after acute stress: A behavioral, morphological and molecular study 

    Aguayo, Felipe I.; Tejos-Bravo, Macarena; Díaz-Véliz, Gabriela; Pacheco, Aníbal; García-Rojo, Gonzalo; Corrales, Wladimir; Olave, Felipe A.; Aliaga-Rojas, Esteban; Ulloa, José L.; Avalos, Ana M.; Román-Albasini, Luciano; Rojas, Paulina S.; Fiedler, Jenny L. (2018)
    Several studies have shown that a single exposure to stress may improve or impair learning and memory processes, depending on the timing in which the stress event occurs with relation to the acquisition phase. However, to ...

  • The ROCK inhibitor fasudil prevents chronic restraint stress-induced depressive-like behaviors and dendritic spine loss in rat hippocampus 

    Aliaga-Rojas, Esteban; García-Rojo, Gonzalo; Fresno, Cristóbal; Vilches, Natalia; Mora, Sergio; Tejos, Macarena; Díaz-Véliz, Gabriela; Aguayo, Felipe I.; Fiedler, Jenny L.; Parra, Claudio S.; Parra-Fiedler, Nicolás; Rojas, Paulina S.; Pacheco, Aníbal (2017)
    Background: Dendritic arbor simplification and dendritic spine loss in the hippocampus, a limbic structure implicated in mood disorders, are assumed to contribute to symptoms of depression. These morphological changes imply ...