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Listar por materia "Helicobacter pylori"

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  • Gastric tumor microenvironment 

    Rojas, Armando ORCID; Araya, Paulina; González-Bonet, Ileana; Morales, Erik (2020)
    A compelling body of evidence has demonstrated that gastric cancer has a very particular tumor microenvironment, a signature very suitable to promote tumor progression and metastasis. Recent investigations have provided ...

  • Helicobacter pylori infection and lung cancer: 
New insights and future challenges 

    González-Bonet, Ileana; Araya, Paulina; Rojas, Armando ORCID (2018)
    Helicobacter pylori (H. pylori) is the causative agent of chronic gastritis and peptic ulcer diseases and is an important risk factor for the development functional dyspepsia, peptic ulceration, gastric adenocarcinoma and ...

  • Lysyl oxidase isoforms in gastric cancer 

    Delgado-López, Fernando; Araya, Paulina; González-Bonet, Ileana; Morales-Mejías, Erik; Pérez-Castro, Ramón; Romero, Jacqueline; Rojas, Armando ORCID; Añazco-Oyarzún, Carolina (2016)
    Gastric cancer (GC) is the fifth most frequent cancer in the world and shows the highest incidence in Latin America and Asia. An increasing amount of evidence demonstrates that lysyl oxidase isoforms, a group of extracellular ...

  • Morfología y repercusiones diagnóstico-terapéuticas de las lesiones preneoplásicas gástricas 

    Sotelo, Sergio; Manterola, Carlos (2019)
    El carcinoma gástrico (CG) de tipo intestinal se origina en un epitelio displásico, que a su vez se desarrolla en medio de una atrofia gástrica (AG) y metaplasia intestinal (MI). La infección por Helicobacter pylori (HP) ...

  • Pathogenic potential of Helicobacter pylori strains can explain differences in H. pylori associated diseases rates from Chile and Cuba 

    González-Bonet, Ileana; González, Lidice; Rojas, Armando ORCID; Rodríguez, Boris L.; Romero, Jacqueline; Reyes, Orlando; Morales, Erik; Alonso, Jordis; Pérez-Castro, Ramón; Sabatier, Carlos A.; Valdés, Eliana; Torres, Linio E.; Cofré, Cecilia (2019)
    Background: The prevalence of Helicobacter pylori-related diseases varies geographically and it is partially determined by the virulence of the circulating strains. Cuba and Chile exhibit different gastric cancer rates, ...

  • Patrón EPIYA en cepas de Helicobacter pylori CagA positivas en pacientes del Hospital Regional de Talca 

    González-Bonet, Ileana; Romero-Elias, María; Morales-Mejías, Erik; Valdez-Moyano, Eliana; Cofré-Loyola, Cecilia; Manques-Maldonado, Belarmino; Rojas, Armando ORCID (2017)
    Background: The clinical outcome of Helicobacter pylori (H. pylori) infection has been related to the presence of CagA protein. This protein is highly polymorphic and its oncogenic ability depends on the number and type ...

  • Pattern recognition receptors and their roles in the host response to helicobacter pylori infection 

    Gonzalez, Ileana; Araya, Paulina; Schneider, Iván; Lindner-Sanhueza, Cristian; Rojas, Armando ORCID (2021)
    Helicobacter pylori (H. pylori) infection is highly prevalent, affecting 4.4 billion people globally. This pathogen is a risk factor in the pathogenesis of more than 75% of worldwide cases of gastric cancer. Pattern ...

  • Unveiling novel urease inhibitors for Helicobacter pylori: A multi-methodological approach from virtual screening and ADME to molecular dynamics simulations 

    Valenzuela-Hormazabal, Paulina; Sepúlveda, Romina V.; Alegría-Arcos, Melissa; Valdés-Muñoz, Elizabeth; Rojas-Pérez, Víctor; González-Bonet, Ileana; Suardíaz, Reynier; Galarza, Christian; Morales, Natalia; Leddermann, Verónica; Castro, Ricardo I.; Benso, Bruna; Urra, Gabriela; Hernández-Rodríguez, Erix W.; Bustos, Daniel (2024)
    Helicobacter pylori (Hp) infections pose a global health challenge demanding innovative therapeutic strategies by which to eradicate them. Urease, a key Hp virulence factor hydrolyzes urea, facilitating bacterial survival ...