Listar por materia "K2P channels"
Mostrando publicaciones 1-3 de 3
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Brief tutorial to evaluate molecular cavities in large conformational ensembles: a K2P channel study case
(2021)In structural bioinformatics, computational biology, or any other field where is important to assess cavities, clefts, pores, or grooves in a macromolecular system, it is imperative to perform this evaluation over a ...
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Differential expression of two-pore domain potassium channels in rat cerebellar granule neurons
(2014)Two pore domain potassium (K2P) channels are mostly present in the central nervous system (CNS) where they play important roles in modulating neuronal excitability. K2P channels give rise to background K+ currents (IKSO) ...
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Elucidating the structural basis of the intracellular pH sensing mechanism of TASK-2 K2P channels
(2020)Two-pore domain potassium (K2P) channels maintain the cell’s background conductance by stabilizing the resting membrane potential. They assemble as dimers possessing four transmembrane helices in each subunit. K2P channels ...