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Listar por materia "RAGE"

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  • Cross-talk between platelet and tumor microenvironment: Role of multiligand/RAGE axis in platelet activation 

    Rojas, Armando ORCID; Fuentes, Eduardo; Palomo, Iván (2016)
    While platelets are well known to play a central role in hemostasis and thrombosis, there is emerging experimental evidence to suggest that they also mediate tumor cell growth, angiogenesis and metastasis. The receptor for ...

  • Dietary advanced glycation end products and their role in health and disease 

    Rojas, Armando ORCID; Uribarri, Jaime; Del Castillo, María Dolores; De la Maza, María Pía; Filip, Rosana; Gugliucci, Alejandro; Luevano Contreras, Claudia; Macías-Cervantes, Maciste H.; Markowicz Bastos, Deborah H.; Medrano, Alejandra; Menini, Teresita; Portero-Otin, Manuel; Rodrigues Sampaio, Geni; Wrobel, Kazimierz; Wrobel, Katarzyna; Garay-Sevilla, Ma. Eugenia (2015)
    Over the past 2 decades there has been increasing evidence supporting an important contribution from food-derived advanced glycation end products (AGEs) to the body pool of AGEs and therefore increased oxidative stress and ...

  • Dietary AGEs as exogenous boosters of inflammation 

    Garay-Sevilla, Ma. Eugenia; Rojas, Armando ORCID; Portero-Otin, Manuel; Uribarri, Jaime (2021)
    Most chronic modern non-transmissible diseases seem to begin as the result of low-grade inflammation extending over prolonged periods of time. The importance of diet as a source of many pro-inflammatory compounds that could ...

  • Extracellular matrix glycation and receptor for advanced glycation end-products activation: A missing piece in the puzzle of the association between diabetes and cancer 

    Rojas, Armando ORCID; Añazco-Oyarzún, Carolina; González-Bonet, Ileana; Araya, Paulina (2018)
    A growing body of epidemiologic evidence suggests that people with diabetes are at a significantly higher risk of many forms of cancer. However, the molecular mechanisms underlying this association are not fully understood. ...

  • NF-κB signaling pathway as target for antiplatelet activity 

    Rojas, Armando ORCID; Fuentes, Eduardo; Palomo, Iván (2016)
    In different nucleated cells, NF-κB has long been considered a prototypical proinflammatory signaling pathway with the expression of proinflammatory genes. Although platelets lack a nucleus, a number of functional ...

  • Polymorphisms −374 T/A and −429 T/C of the receptor for advanced glycation end-products (RAGE) and serum levels of RAGE (sRAGE) are not associated with metabolic syndrome 

    González-Guerrero, Diana E.; Lazo-de-la-Vega-Monroy, María L.; Gómez-Ojeda, Armando; Luévano-Contreras, Claudia; Rojas, Armando ORCID; Garay-Sevilla, Ma. Eugenia (2023)
    RAGE is a multi-ligand transmembrane glycoprotein that promotes biological signals associated with inflammatory responses and degenerative diseases. sRAGE is a soluble variant that has been proposed as an inhibitor of RAGE ...

  • Role of multiligand/RAGE axis in platelet activation 

    Rojas, Armando ORCID; Fuentes, Eduardo; Palomo, Iván (2014)
    In the context of plaque progression, platelet hyperactivity associated with hyperlipidemia contributes to the development of a pro-thrombotic state. In this context, it has been demonstrated that advanced glycation end ...

  • The immunobiology of the receptor of advanced glycation end-products: Trends and challenges 

    González-Bonet, Ileana; Romero, Jacqueline; Rodríguez, Boris L.; Pérez-Castro, Ramón; Rojas, Armando ORCID (2013)
    Pattern-recognition receptors have been highly conserved in evolution. They recognize danger signals including both pathogen- and damage-associated molecular patterns, also known as alarmins. Several signaling pathways ...

Sistema de Bibliotecas de la Universidad Católica del Maule, 2017
Campus San Miguel, Talca. Teléfono (56) (71) 2-203 359
Campus Nuestra Señora del Carmen, Curicó. Teléfono (56) (75) 2203 111
Campus San Isidro, Los Niches. Teléfono (56) (75) 2203 617