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Browsing by Subject "Structural biology"

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  • Dynamin‑2 R465W mutation induces long range perturbation in highly ordered oligomeric structures 

    Hinostroza, Fernando; Neely, Alan; Araya‑Duran, Ingrid; Marabolí, Vanessa; Canan, Jonathan; Rojas, Maximiliano; Aguayo, Daniel; Latorre, Ramón; González‑Nilo, Fernando D.; Cárdenas, Ana M. (2020)
    High order oligomers are crucial for normal cell physiology, and protein function perturbed by missense mutations underlies several autosomal dominant diseases. Dynamin-2 is one of such protein forming helical oligomers ...