Listar Artículos Científicos por autor 

Listar Artículos Científicos por autor

Mostrando publicaciones 1-4 de 4

  • Dynamin‑2 R465W mutation induces long range perturbation in highly ordered oligomeric structures 

    Hinostroza, Fernando; Neely, Alan; Araya‑Duran, Ingrid; Marabolí, Vanessa; Canan, Jonathan; Rojas, Maximiliano; Aguayo, Daniel; Latorre, Ramón; González‑Nilo, Fernando D.; Cárdenas, Ana M. (2020)
    High order oligomers are crucial for normal cell physiology, and protein function perturbed by missense mutations underlies several autosomal dominant diseases. Dynamin-2 is one of such protein forming helical oligomers ...

  • Large conductance voltage-and calcium-activated K+ (BK) channel in health and disease 

    Echeverría, Felipe; Gonzalez-Sanabria, Naileth; Alvarado-Sanchez, Rosangelina; Fernández, Miguel; Castillo, Karen; Latorre, Ramón (2024)
    Large Conductance Voltage- and Calcium-activated K+ (BK) channels are transmembrane pore-forming proteins that regulate cell excitability and are also expressed in non-excitable cells. They play a role in regulating vascular ...

  • The bisphosphonate zoledronic acid is a TRPV1 channel inhibitor 

    Castillo, Karen; Duarte, Yorley; Segura, Ignacio A.; Tricarico, Domenico; Chavez, Andres; Latorre, Ramón; Meza, Rodrigo; Ancaten, Carlos; Carvajal-Zamorano, Karina; Scala, Rosa (2023)
    The heat and capsaicin sensor, the transient receptor potential vanilloid type 1 (TRPV1) channel, is critically involved in pain sensation. Using compounds that activate TRPV1, such as capsaicin (CAP), produces analgesic ...

  • TRPM8 channel promotes the osteogenic differentiation in human bone marrow mesenchymal stem cells 

    Henao, Juan C.; Grismaldo, Adriana; Barreto, Alfonso; Rodríguez-Pardo, Viviana M.; Mejía-Cruz, Claudia C.; Leal-Garcia, Efrain; Pérez-Núñez, Rafael; Rojas, Patricio; Latorre, Ramón; Carvacho-Contreras, Ingrid; Torres, Yolima P. (2021)
    Various families of ion channels have been characterized in mesenchymal stem cells (MSCs), including some members of transient receptor potential (TRP) channels family. TRP channels are involved in critical cellular processes ...