Listar Artículos Científicos por autor
Mostrando publicaciones 1-3 de 3
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Antidepressant-relevant behavioral and synaptic molecular effects of long-term fasudil treatment in chronically stressed male rats
Román-Albasini, Luciano; Díaz-Véliz, Gabriela; Olave, Felipe A.; Aguayo, Felipe; García-Rojo, Gonzalo; Corrales, Wladimir; Silva, Juan P.; Ávalos, Ana; Rojas, Paulina S.; Aliaga-Rojas, Esteban; Fiedler, Jenny L. (2020)Several lines of evidence suggest that antidepressant drugs may act by modulating neuroplasticity pathways in key brain areas like the hippocampus. We have reported that chronic treatment with fasudil, a Rho-associated ...
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Deletion of hippocampal Glucocorticoid receptors unveils sex-biased microRNA expression and neuronal morphology alterations in mice
Tejos-Bravo, Macarena; Oakley, Robert H.; Whirledge, Shannon D.; Corrales, Wladimir; Silva, Juan P.; García-Rojo, Gonzalo; Toledo, Jorge; Sanchez, Wendy; Román-Albasini, Luciano; Aliaga-Rojas, Esteban; Aguayo, Felipe; Olave, Felipe A.; Marcaja-Coutinho, Vinicius; Cidlowski, John A.; Fiedler, Jenny L. (2021)Sex differences in the brain have prompted many researchers to investigate the underlying molecular actors, such as the glucocorticoid receptor (GR). This nuclear receptor controls gene expression, including microRNAs ...
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Sex-dependent changes of miRNA levels in the hippocampus of adrenalectomized rats following acute corticosterone administration
Corrales, Wladimir; Silva, Juan P.; Parra, Claudio S.; Olave, Felipe A.; Aguayo, Felipe; Román-Albasini, Luciano; Aliaga-Rojas, Esteban; Venegas-Zamora, Leslye; Avalos, Ana M.; Rojas, P.S.; Marcaja-Coutinho, Vinicius; Oakley, Robert H.; Cidlowski, John A.; Fiedler, Jenny L. (2021)We explored sex-biased effects of the primary stress glucocorticoid hormone corticosterone on the miRNA expression profile in the rat hippocampus. Adult adrenalectomized (ADX) female and male rats received a single ...