• Deletion of hippocampal Glucocorticoid receptors unveils sex-biased microRNA expression and neuronal morphology alterations in mice 

    Tejos-Bravo, Macarena; Oakley, Robert H.; Whirledge, Shannon D.; Corrales, Wladimir; Silva, Juan P.; García-Rojo, Gonzalo; Toledo, Jorge; Sanchez, Wendy; Román-Albasini, Luciano; Aliaga-Rojas, Esteban; Aguayo, Felipe; Olave, Felipe A.; Marcaja-Coutinho, Vinicius; Cidlowski, John A.; Fiedler, Jenny L. (2021)
    Sex differences in the brain have prompted many researchers to investigate the underlying molecular actors, such as the glucocorticoid receptor (GR). This nuclear receptor controls gene expression, including microRNAs ...

  • Sex-dependent changes of miRNA levels in the hippocampus of adrenalectomized rats following acute corticosterone administration 

    Corrales, Wladimir; Silva, Juan P.; Parra, Claudio S.; Olave, Felipe A.; Aguayo, Felipe; Román-Albasini, Luciano; Aliaga-Rojas, Esteban; Venegas-Zamora, Leslye; Avalos, Ana M.; Rojas, P.S.; Marcaja-Coutinho, Vinicius; Oakley, Robert H.; Cidlowski, John A.; Fiedler, Jenny L. (2021)
    We explored sex-biased effects of the primary stress glucocorticoid hormone corticosterone on the miRNA expression profile in the rat hippocampus. Adult adrenalectomized (ADX) female and male rats received a single ...