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Physical capability markers used to define sarcopenia and their association with cardiovascular and respiratory outcomes and all-cause mortality: a prospective study from UK biobank
(2020)
Introduction: It is unclear what combinations of physical capability markers used to define sarcopenia have the strongest associations with health outcomes. Aim: To compare the associations between different combinations ...
Alzheimer's disease susceptibility gene Apolipoprotein E (APOE) and blood biomarkers in UK Biobank (N = 395,769)
(2020)
Background: Alzheimer's disease (AD) is a neurodegenerative condition where the underlying etiology is still unclear. Investigating the potential influence of apolipoprotein E (APOE), a major genetic risk factor, on common ...
Vegetarians, fish, poultry, and meat-eaters: Who has higher risk of cardiovascular disease incidence and mortality? A prospective study from UK Biobank
(2021)
Aims: To compare the incidence and mortality risk for cardiovascular diseases (CVD) [CVD and also ischaemic heart disease (IHD), myocardial infarction (MI), stroke, and heart failure (HF)] among people with different types ...
Comparison of two different frailty measurements and risk of hospitalisation or death from COVID-19: findings from UK Biobank
(2020)
Background. Frailty has been associated with worse prognosis following COVID-19 infection. While several studies have reported the association between frailty and COVID-19 mortality or length of hospital stay, there have ...
Are people with metabolically healthy obesity really healthy? A prospective cohort study of 381,363 UK Biobank participants
(2021)
Aims/hypothesis: People with obesity and a normal metabolic profile are sometimes referred to as having ‘metabolically healthy obesity’ (MHO). However, whether this group of individuals are actually ‘healthy’ is uncertain. ...
Associations between grip strength and incident type 2 diabetes: findings from the UK Biobank prospective cohort study
(2021)
Introduction: Grip strength has been associated with chronic diseases and mortality. However, current evidence of the association between grip strength and incident type 2 diabetes mellitus (T2DM) is controversial. The aim ...
Association between device-measured physical activity and incident heart failure: a prospective cohort study of 94 739 uk biobank participants
(2022)
Background:
Studies of objectively measured physical activity (PA) have investigated acute cardiovascular outcomes but not heart failure (HF), an emerging chronic condition. This study aimed to investigate the dose-response ...
Associations of fat and carbohydrate intake with cardiovascular disease and mortality: prospective cohort study of UK Biobank participants
(2020)
Objective: To investigate the association of macronutrient intake with all cause mortality and cardiovascular disease (CVD), and the implications for dietary advice.
Design: Prospective population based study.
Setting: ...
Understanding how much TV is too much: a nonlinear analysis of the association between television viewing time and adverse health outcomes
(2020)
Objective: To inform potential guideline development, we investigated nonlinear associations between television viewing time (TV time) and adverse health outcomes.
Methods: From 2006 to 2010, 490,966 UK Biobank participants, ...
Identifying the biomarker profile of pre-frail and frail people: a cross-sectional analysis from UK biobank
(2023)
Objective: This study aimed to compare the biomarker profile of pre-frail and frail adults in the UK Biobank cohort by sex. Methods: In total, 202,537 participants (67.8% women, aged 37 to 73 years) were included in this ...