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dc.contributor.authorRojas, Armando
dc.contributor.authorPérez-Castro, Ramón
dc.contributor.authorGonzález-Bonet, Ileana
dc.contributor.authorDelgado-López, Fernando
dc.contributor.authorRomero, Jacqueline
dc.contributor.authorRojas, Israel
dc.date.accessioned2017-11-03T20:20:46Z
dc.date.available2017-11-03T20:20:46Z
dc.date.issued2014
dc.identifier.urihttp://repositorio.ucm.cl/handle/ucm/1105
dc.description.abstractCells from innate immune system are activated by the engagement of germ-line encoded patternrecognition receptors (PRRs) in response to the microbial insult. These receptors are able to recognize either the presence of highly conserved microbial components called pathogen-associated molecular patterns or endogenous danger-associated molecular patterns. These danger signals are recognized by different types of (PRRs), including the receptor for advanced glycation end products. This new PRR share both ligands and intracellular signaling with Toll-like receptors and thus may cooperate with each other as essential partners to strength inflammatory response. This review summarizes recent advances in understanding the promiscuity of this receptor as well as its role in the context of innate immunity by triggering an inflammatory response when innate immune cells detect infection or tissue injury.es_CL
dc.language.isoenes_CL
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 Chile*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
dc.sourceInternational Reviews of Immunology, 33, 67-80es_CL
dc.subjectAlarminses_CL
dc.subjectDanger-associated molecular patternses_CL
dc.subjectInnate immunityes_CL
dc.subjectPattern recognition receptorses_CL
dc.subjectReceptor for advanced glycation end productses_CL
dc.subjectSeptic inflammationes_CL
dc.titleThe emerging role of the receptor for advanced glycation end products on innate immunityes_CL
dc.typeArticlees_CL
dc.ucm.facultadFacultad de Medicinaes_CL
dc.ucm.indexacionScopuses_CL
dc.ucm.indexacionIsies_CL
dc.ucm.urisibib2.ucm.cl:2048/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=mdc&AN=24266871&lang=es&site=eds-live&scope=sitees_CL
dc.ucm.doidoi.org/10.3109/08830185.2013.849702es_CL


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Atribución-NoComercial-SinDerivadas 3.0 Chile
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