El consumo de frutas y hortalizas ayuda a prevenir el daño endotelial

Palomo, Iván; Fuentes, Eduardo; Moore-Carrasco, Rodrigo; González, Daniel R.; Rojas, Armando; Padro, Teresa; Badimon, Lina

Mostrar el registro sencillo de la publicación

dc.contributor.author	Palomo, Iván
dc.contributor.author	Fuentes, Eduardo
dc.contributor.author	Moore-Carrasco, Rodrigo
dc.contributor.author	González, Daniel R.
dc.contributor.author	Rojas, Armando
dc.contributor.author	Padro, Teresa
dc.contributor.author	Badimon, Lina
dc.date.accessioned	2017-12-13T12:47:57Z
dc.date.available	2017-12-13T12:47:57Z
dc.date.issued	2011
dc.identifier.uri	http://repositorio.ucm.cl/handle/ucm/1610
dc.description.abstract	The endothelium helps to maintain the normal structure and homeostasis of the vasculature. However, chronic exposure to cardiovascular (CV) risk factors causes endothelial dysfunction, a phenomenon that is characterized by inflammation, reduced bioavailability of nitric oxide (NO) and a prothrombotic state. Epidemiological studies have shown that regular consumption of fruits and vegetables reduces CV risk, which has caused interest in knowing the bioactive compounds and the mechanisms involved. Among the components that protect the endothelium are antioxidants (vitamin C, vitamin E and polyphenols) and polyunsaturated fatty acids. Vitamin C and E promote vasodilatation protecting NO by blocking the reactive oxygen species (ROS). Polyphenols improve endothelial function primarily by increasing levels of NO, and inhibition of angiogenesis and platelet activation. Diets rich in polyunsaturated fatty acids have shown beneficial effects by reducing the gene expression of cyclooxygenase-2 and the expression of cell adhesion molecules. This review mainly highlights the current understanding of endothelial dysfunction and the protective effect of endothelial cells by bioactive components of fruits and vegetables.	es_CL
dc.language.iso	es	es_CL
dc.rights	Atribución-NoComercial-SinDerivadas 3.0 Chile	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/cl/	*
dc.source	Revista Chilena de Nutrición, 38(3), 343-355	es_CL
dc.subject	Cardiovascular diseases	es_CL
dc.subject	Atherosclerosis	es_CL
dc.subject	Endothelial dysfunction	es_CL
dc.subject	Biomarkers	es_CL
dc.subject	Fruit	es_CL
dc.subject	Vegetables	es_CL
dc.subject	Polyphenols	es_CL
dc.title	El consumo de frutas y hortalizas ayuda a prevenir el daño endotelial	es_CL
dc.title.alternative	Consumption of fruits and vegetables in the prevention of endothelial damage	es_CL
dc.type	Article	es_CL
dc.ucm.facultad	Facultad de Medicina	es_CL
dc.ucm.indexacion	Scopus	es_CL
dc.ucm.indexacion	Scielo	es_CL
dc.ucm.doi	dx.doi.org/10.4067/S0717-75182011000300010	es_CL