Abstract: The objective of this paper is to evaluate and to simulate the cogeneration process applied to an apartment building in the Polanco area (Mexico). Considering the building’s electric, thermal demand and consumption data, the cogeneration process model was simulated using Thermoflow© software (Thermoflow Inc., Jacksonville, FL, USA), in order to cover 1.1 MW of electric demand and to supply the thermal needs of hot water, heating, air conditioning and heating pool. As a result of analyzing various schemes of cogeneration, the most efficient scheme consists of the use of a gas turbine (Siemens model SGT-100-1S), achieving a cycle with efficiency of 84.4% and a heat rate of 14,901 kJ/kWh. The economic results of this evaluation show that it is possible to implement the cogeneration in the building with a natural gas price below US$0.014/kWh. The use of financing schemes makes the economic results more attractive. Furthermore, the percentage of the turbine load effect on the turbine load net power, cogeneration efficiency, chimney flue gas temperature, CO2 emission, net heat ratio, turbine fuel flow and after burner fuel flow was also studied.