Device-measured physical activity and incident afective disorders

Ho, Frederick; Petermann-Rocha, Fanny; Parra‑Soto, Solange; Boonpor, Jirapitcha; Gill, Jason M.R.; Gray, S.R.; Pell, J.P.; Celis-Morales, Carlos

Mostrar el registro sencillo de la publicación

dc.contributor.author	Ho, Frederick
dc.contributor.author	Petermann-Rocha, Fanny
dc.contributor.author	Parra‑Soto, Solange
dc.contributor.author	Boonpor, Jirapitcha
dc.contributor.author	Gill, Jason M.R.
dc.contributor.author	Gray, S.R.
dc.contributor.author	Pell, J.P.
dc.contributor.author	Celis-Morales, Carlos
dc.date.accessioned	2022-10-18T17:21:09Z
dc.date.available	2022-10-18T17:21:09Z
dc.date.issued	2022
dc.identifier.uri	http://repositorio.ucm.cl/handle/ucm/4101
dc.description.abstract	Background: Studies on physical activity (PA) and mental health are largely limited to self-reported PA. This study aims to use prospective cohort data to investigate the association between device-measured PA and afective disorders. Methods: A total of 37,327 participants from UK Biobank who had not had any prior afective disorder diagnoses were included in this prospective cohort study. Wrist-worn accelerometers were used to measure total, light (LPA), moderate (MPA), and vigorous (VPA) PA. Associations between PA domains and afective disorders were analysed using penalised splines in Cox proportional hazard models. Analyses were adjusted for other intensity-specifc PA and sociodemographic and lifestyle factors. Sensitivity analyses were conducted adjusting for body mass index and longstanding illnesses as well as excluding events in the frst 2 years of follow-up. Preventable fractions for the popula‑ tion were estimated for MPA and VPA. Results: Over a median follow-up of 6.8 years, 1262 (3.4%) individuals were diagnosed with afective disorders. Replacing 30 min of sedentary behaviour in a week with MPA (HR 0.95, 95% CI 0.94–0.97) or VPA (HR 0.91, 95% CI 0.85–0.98) was associated with lower risk of afective behaviours, up to 500 and 120 min of MPA and VPA. Assuming causality, 5.14% and 18.88% of afective disorders could have been prevented if MPA ≥150 min/week and VPA ≥75 min/week were achieved, respectively, across the study population. Conclusions: Device-measured MPA and VPA were associated with lower risk of afective disorders. The potential mental health benefts of MPA continue to accrue above the current World Health Organization recommendation.	es_CL
dc.language.iso	en	es_CL
dc.rights	Atribución-NoComercial-SinDerivadas 3.0 Chile	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/cl/	*
dc.source	European Journal of Forest Research, 141, 753-767	es_CL
dc.subject	Accelerometery	es_CL
dc.subject	Physical activity	es_CL
dc.subject	Depression	es_CL
dc.subject	Anxiety	es_CL
dc.subject	Mental health	es_CL
dc.title	Device-measured physical activity and incident afective disorders	es_CL
dc.type	Article	es_CL
dc.ucm.indexacion	Scopus	es_CL
dc.ucm.indexacion	Isi	es_CL
dc.ucm.doi	doi.org/10.1186/s12916-022-02484-0	es_CL