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Frailty index as a predictor of mortality in middle-aged and older people: a prospective analysis of Chilean adults

dc.contributor.authorDiaz-Toro, Felipe
dc.contributor.authorNazar, Gabriela
dc.contributor.authorTroncoso-Pantoja, Claudia
dc.contributor.authorConcha-Cisternas, Yeny
dc.contributor.authorLeiva-Ordoñez, Ana María
dc.contributor.authorMartinez-Sanguinetti, María Adela
dc.contributor.authorParra‑Soto, Solange
dc.contributor.authorLasserre-Laso, Nicole
dc.contributor.authorCigarroa, Igor
dc.contributor.authorMardones, Lorena
dc.contributor.authorVásquez-Gómez, Jaime A.
dc.contributor.authorPetermann-Rocha, Fanny
dc.contributor.authorDiaz-Martinez, Ximena
dc.contributor.authorCelis-Morales, Carlos
dc.date.accessioned2023-03-08T12:58:23Z
dc.date.available2023-03-08T12:58:23Z
dc.date.issued2023
dc.identifier.urihttp://repositorio.ucm.cl/handle/ucm/4483
dc.description.abstractWe aimed to investigate the association between frailty status and all-cause mortality in middle-aged and older people. We included 2661 individuals aged ≥ 35 from the Chilean National Health Survey 2009–2010. Mortality was determined through linkage with the Chilean Civil Registry and Identification. A 36-item frailty index (FI) was used to assess the frailty status. Associations between frailty status and all-cause mortality were assessed using Kaplan–Meier and Cox proportional hazard models adjusted for sociodemographic and lifestyle factors. A non-linear association was investigated using penalized cubic splines fitted in the Cox models. During an 8.9 median follow-up (interquartile range of 8.6–9.0), 308 individuals died (11.5%). Lower survival rates were observed in frail individuals compared to pre-frail and robust people (log-rank < 0.001). Compared with robust individuals, frail people had a higher mortality risk (HR: 2.35 [95% CI: 1.57 to 3.51]). Frail middle-aged individuals had a higher risk of dying independently of major risk factors.es_CL
dc.language.isoenes_CL
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 Chile*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
dc.sourceInternational Journal of Environmental Research and Public Health, 20(2), 1195es_CL
dc.subjectFrailtyes_CL
dc.subjectMortalityes_CL
dc.subjectMiddle-agedes_CL
dc.subjectChilees_CL
dc.titleFrailty index as a predictor of mortality in middle-aged and older people: a prospective analysis of Chilean adultses_CL
dc.typeArticlees_CL
dc.ucm.indexacionScopuses_CL
dc.ucm.indexacionIsies_CL
dc.ucm.urimdpi.com/1660-4601/20/2/1195es_CL
dc.ucm.doidoi.org/10.3390/ijerph20021195es_CL


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