Mostrar el registro sencillo de la publicación
Lysyl oxidase isoforms in gastric cancer
| dc.contributor.author | Delgado-López, Fernando | |
| dc.contributor.author | Araya, Paulina | |
| dc.contributor.author | González-Bonet, Ileana | |
| dc.contributor.author | Morales-Mejías, Erik | |
| dc.contributor.author | Pérez-Castro, Ramón | |
| dc.contributor.author | Romero, Jacqueline | |
| dc.contributor.author | Rojas, Armando | |
| dc.contributor.author | Añazco-Oyarzún, Carolina | |
| dc.date.accessioned | 2017-10-12T13:05:22Z | |
| dc.date.available | 2017-10-12T13:05:22Z | |
| dc.date.issued | 2016 | |
| dc.identifier.uri | http://repositorio.ucm.cl/handle/ucm/456 | |
| dc.description.abstract | Gastric cancer (GC) is the fifth most frequent cancer in the world and shows the highest incidence in Latin America and Asia. An increasing amount of evidence demonstrates that lysyl oxidase isoforms, a group of extracellular matrix crosslinking enzymes, should be considered as potential biomarkers and therapeutic targets in GC. In this review, we focus on the expression levels of lysyl oxidase isoforms, its functions and the clinical implications in GC. Finding novel proteins related to the processing of these extracellular matrix enzymes might be helpful in the design of new therapies, which, in combination with classic pharmacology, could be used to delay the progress of this aggressive cancer and offer a wider temporal window for clinical intervention. | es_CL |
| dc.language.iso | en | es_CL |
| dc.rights | Atribución-NoComercial-SinDerivadas 3.0 Chile | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | * |
| dc.source | Biomarkers in Medicine, 10(9), 987-998 | es_CL |
| dc.subject | Basement membrane | es_CL |
| dc.subject | Collagen | es_CL |
| dc.subject | Copper depletion | es_CL |
| dc.subject | Extracellular matrix | es_CL |
| dc.subject | Fibrosis | es_CL |
| dc.subject | Gastric cancer | es_CL |
| dc.subject | Helicobacter pylori | es_CL |
| dc.subject | Lysyl oxidase isoforms | es_CL |
| dc.subject | Tumor promoter | es_CL |
| dc.subject | Tumor suppressor | es_CL |
| dc.title | Lysyl oxidase isoforms in gastric cancer | es_CL |
| dc.type | Article | es_CL |
| dc.ucm.facultad | Facultad de Medicina | es_CL |
| dc.ucm.indexacion | Scopus | es_CL |
| dc.ucm.indexacion | Isi | es_CL |
| dc.ucm.uri | www.futuremedicine.com/doi/abs/10.2217/bmm-2016-0075?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=bmm | es_CL |
| dc.ucm.doi | doi.org/10.2217/bmm-2016-0075 | es_CL |
Ficheros en la publicación
| Ficheros | Tamaño | Formato | Ver |
|---|---|---|---|
|
No hay ficheros asociados a esta publicación. |
|||
Esta publicación aparece en la(s) siguiente(s) colección(ones)
Excepto si se señala otra cosa, la licencia de la publicación se describe como Atribución-NoComercial-SinDerivadas 3.0 Chile