The involvement of antioxidants in cognitive decline and neurodegeneration: Mens Sana in Corpore Sano

Nazzi, Claudio; Avenanti, Alessio; Battaglia, Simone

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dc.contributor.author	Nazzi, Claudio
dc.contributor.author	Avenanti, Alessio
dc.contributor.author	Battaglia, Simone
dc.date.accessioned	2024-08-07T15:14:12Z
dc.date.available	2024-08-07T15:14:12Z
dc.date.issued	2024
dc.identifier.uri	http://repositorio.ucm.cl/handle/ucm/5595
dc.description.abstract	With neurodegenerative disorders being on the rise, a great deal of research from multiple fields is being conducted in order to further knowledge and propose novel therapeutic interventions. Among these investigations, research on the role of antioxidants in contrasting cognitive decline is putting forward interesting and promising results. In this review, we aim to collect evidence that focused on the role of a variety of antioxidants and antioxidant-rich foods in improving or stabilizing cognitive functions, memory, and Alzheimer’s disease, the most common neurodegenerative disorder. Specifically, we considered evidence collected on humans, either through longitudinal studies or randomized, placebo-controlled ones, which evaluated cognitive performance, memory abilities, or the progression level of neurodegeneration. Overall, despite a great deal of variety between study protocols, cohorts of participants involved, neuropsychological tests used, and investigated antioxidants, there is a solid trend that suggests that the properties of antioxidants may be helpful in hampering cognitive decline in older people. Thus, the help of future research that will further elucidate the role of antioxidants in neuroprotection will lead to the development of novel interventions that will take into account such findings to provide a more global approach to treating neurodegenerative disorders.	es_CL
dc.language.iso	en	es_CL
dc.rights	Atribución-NoComercial-SinDerivadas 3.0 Chile	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/cl/	*
dc.source	Antioxidants, 13(6), 701	es_CL
dc.subject	Memory	es_CL
dc.subject	Cognitive impairment	es_CL
dc.subject	Alzheimer’s disease	es_CL
dc.subject	Neurodegeneration	es_CL
dc.title	The involvement of antioxidants in cognitive decline and neurodegeneration: Mens Sana in Corpore Sano	es_CL
dc.type	Article	es_CL
dc.ucm.indexacion	Scopus	es_CL
dc.ucm.indexacion	Isi	es_CL
dc.ucm.uri	mdpi.com/2076-3921/13/6/701	es_CL
dc.ucm.doi	doi.org/10.3390/antiox13060701	es_CL