Listar Producción Académica por autor
Mostrando publicaciones 1-4 de 4
-
Colloidal carbon stimulation of Kupffer cells triggers Nrf2 activation in the isolated perfused rat liver
Núñez, Bárbara; Vargas, Romina; Castillo-Montecinos, Iván; Videla, Luis A. (2012)Activation of transcription factor Nrf2 was investigated in the isolated perfused rat liver infused with 0.5 mg of colloidal carbon (CC)/ml for 5–15 min to stimulated Kupffer cell function. Infusion of CC enhanced liver ...
-
Maresin 1, a proresolving lipid mediator, ameliorates liver ischemia-reperfusion injury and stimulates hepatocyte proliferation in Sprague-Dawley rats
Soto, Gonzalo; Rodríguez, María J.; Fuentealba, Roberto; Treuer, Adriana V.; Castillo-Montecinos, Iván; González, Daniel R.; Zúñiga-Hernández, Jessica (2020)Maresin-1 (MaR1) is a specialized pro-resolving mediator, derived from omega-3 fatty acids, whose functions are to decrease the pro-inflammatory and oxidative mediators, and also to stimulate cell division. We investigated ...
-
Pro-resolving lipid mediator resolvin E1 mitigates the progress of diethylnitrosamine-induced liver fibrosis in sprague-dawley rats by attenuating fibrogenesis and restricting proliferation
Castillo-Montecinos, Iván; Herrera, Francisca; Orrego, Roxana; Zúñiga-Hernández, Jessica; Donoso-Torres, Wendy; Rodríguez, María J.; González, Daniel R. (2020)Liver fibrosis is a complex process associated to most types of chronic liver disease, which is characterized by a disturbance of hepatic tissue architecture and the excessive accumulation of extracellular matrix. Resolvin ...
-
Thyroid hormone-induced cytosol-to-nuclear translocation of rat liver Nrf2 is dependent on Kupffer cell functioning
Videla, Luis A.; Cornejo, Pamela; Romanque, Pamela; Santibáñez, Catherine; Castillo-Montecinos, Iván; Vargas, Romina (2012)L-3,3 ,5-triiodothyronine (T3) administration upregulates nuclear factor-E2-related factor 2 (Nrf2) in rat liver, which is redoxsensitive transcription factor mediating cytoprotection. In this work, we studied the role of ...