Browsing Producción Académica by Author "a3eba27b-b057-4f3d-be7c-35c8621425c9"
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Alzheimer's disease susceptibility gene Apolipoprotein E (APOE) and blood biomarkers in UK Biobank (N = 395,769)
Ferguson, Amy C.; Tank, Rachana; Lyall, Laura M.; Ward, Joey; Celis-Morales, Carlos; Strawbridge, Rona; Ho, Frederick; Whelan, Christopher D.; Gill, Jason M.R.; Welsh, Paul; Anderson, Jana J.; Mark, Patrick B.; Mackay, Daniel; Smith, Daniel J.; Pell, J.P.; Cavanagh, Jonathan; Sattar, Naveed; Lyall, Donald (2020)Background: Alzheimer's disease (AD) is a neurodegenerative condition where the underlying etiology is still unclear. Investigating the potential influence of apolipoprotein E (APOE), a major genetic risk factor, on common ...
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How do lifestyle factors modify the association between genetic predisposition and obesity-related phenotypes? a 4-way decomposition analysis using UK Biobank
Zhang, Mengrong; Ward, Joey; Strawbridge, Rona; Celis-Morales, Carlos; Pell, Jill P.; Lyall, Donald; Ho, Frederick (2024)Background Obesity and central obesity are multifactorial conditions with genetic and non-genetic (lifestyle and environmental) contributions. There is incomplete understanding of whether lifestyle modifies the translation ...