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HMGB1 enhances the protumoral activities of M2 macrophages by a RAGE-dependent mechanism
(2016)
The monocyte-macrophage lineage shows a high degree of diversity and plasticity. Once they infiltrate tissues,they may acquire two main functional phenotypes, being known as the classically activated type 1 macrophages ...
Lysyl oxidase isoforms in gastric cancer
(2016)
Gastric cancer (GC) is the fifth most frequent cancer in the world and shows the highest incidence in Latin America and Asia. An increasing amount of evidence demonstrates that lysyl oxidase isoforms, a group of extracellular ...
Patrón EPIYA en cepas de Helicobacter pylori CagA positivas en pacientes del Hospital Regional de Talca
(2017)
Background: The clinical outcome of Helicobacter pylori (H. pylori) infection has been related to the presence of CagA protein. This protein is highly polymorphic and its oncogenic ability depends on the number and type ...
Gallbladder cancer risk and indigenous south american mapuche ancestry: instrumental variable analysis using ancestry-informative markers
(2023)
A strong association between the proportion of indigenous South American Mapuche ancestry and the risk of gallbladder cancer (GBC) has been reported in observational studies. Chileans show the highest incidence of GBC ...