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Inhibition of RAGE Axis signaling: A pharmacological challenge
(2019)
The Receptor for Advanced Glycation End Products (RAGE) is an important cell surface receptor, which belongs to the IgG super family and is now considered as a pattern recognition receptor. Because of its relevance in many ...
HMGB1 decreases CCR-2 expression and migration of M2 macrophages under hypoxia
(2019)
Objective: The hypoxic milieu at tumor microenvironment is able to drive the behavior of infiltrating tumor cells. Considering that hypoxia-mediated HMGB1 release is known to promote tumor growth, as well to enhance the ...